نتایج جستجو برای: multiple sclerosis disease

تعداد نتایج: 2161038  

Journal: :Brain : a journal of neurology 2009
E A Yeh B Weinstock-Guttman M Ramanathan D P Ramasamy L Willis J L Cox R Zivadinov

The purpose of this study was to compare the clinical and quantitative magnetic resonance imaging metrics of paediatric-onset multiple sclerosis to adult-onset multiple sclerosis. It was a prospective comparison of clinical and magnetic resonance imaging characteristics of two paediatric onset multiple sclerosis and two adult onset multiple sclerosis groups that were matched for disease duratio...

Journal: :international clinical neurosciences journal 0
sadegh izadi clinical neurology research center, shiraz university of medical sciences, shiraz, iran saeede khoshniat shiraz university of medical sciences, shiraz, iran

background and purpose: multiple sclerosis (ms) is believed to be an immune-mediated disorder that develops from an interaction of the individual's genetic and as yet unidentified environmental causes. the prevalence of auto-antibodies in multiple sclerosis patients and their clinical associations vary in various studies. the aim of this study was to determine serum auto antibodies in multiple ...

Journal: :مجله علوم اعصاب شفای خاتم 0
mona abdollahi a. islamic azad university, mashhad branch, mashhad, iran b. member of mashhad neuroscience research group of islamic azad university, mashhad branch, mashhad, iran

multiple sclerosis is an autoimmune disease of the central nervous system which is accompanied by demyelinating the neurons. the imbalance between the t cell effectors and t cell regulators is thought to have a role in the pathogenesis of the disease. melatonin is a hormone that is secreted by pineal gland which has an important role in circadian rhythm and immune-modulatory effects. melatonin ...

Journal: :مجله علوم اعصاب شفای خاتم 0
ali shariat razavi medicine faculty, islamic azad university, mashhad branch, mashhad, iran mohammad reza khojasteh medicine faculty, islamic azad university, mashhad branch, mashhad, iran aida java zadeh medicine faculty, islamic azad university, mashhad branch, mashhad, iran sajad sahab negah a. department of neuroscience, mashhad university of medical sciences, mashhad, iran b. shefa neuroscience research center, khatam alanbia hospital, tehran, iranshefa neuroscience research center, khatam alanbia hospital, tehran, iran

neuroinflammation has a significant role in induce of multiple sclerosis (ms) many approaches have been used to treat ms, but none of these methods have not been able to fully improve. one of the methods can suppress inflammation and regenerate the nervous system is the use of cell therapy. using cell therapy in pre-clinic phase can be realized, it's mechanism and potency to suppress neuro...

Journal: :international journal of preventive medicine 0
mohamad reza najafi vahid shaygannajad maryam mirpourian ali gholamrezaei

background: vitamin b12 (cobalamin) deficiency can result in some clinical and paraclinical characteristics similar to what is seen in multiple sclerosis (ms) patients. this study aimed to evaluate the controversial association between vitamin b12 deficiency and ms. methods: we measured serum vitamin b12 in 60 patients with ms and 38 healthy controls. clinical disability was evaluated according...

Journal: :international journal of preventive medicine 0
abbas ghorbani mehri salari vahid shaygannejad rasul norouzi

background: the association between the prevalence of multiple sclerosis (ms) and latitude gradient indicates the importance of environmental factors in ms susceptibility. sunlight’s ultraviolet radiation, its ability to influence melatonin, and an imbalance of melatonin in the central nervous system (cns) may be involved in this process. methods: this case‑control study was conducted in isfaha...

Journal: :iranian journal of immunology 0
mansour salehi department of genetics and molecular biology, school of medicine, school of medicine, isfahan university of medical sciences, isfahan, iran bahram bagherpour department of genetics and molecular biology, school of medicine, school of medicine, isfahan university of medical sciences, isfahan, iran vahid shayghannejad department of neurology, school of medicine, isfahan university of medical sciences, school of medicine, isfahan university of medical sciences, isfahan, iran farzaneh mohebi department of microbiology, islamic azad university, school of medicine, isfahan university of medical sciences, isfahan, iran rasool jafari department of parasitology and mycology, school of medicine, isfahan university of medical sciences, isfahan, iran

background: management of multiple sclerosis (ms) is based on the usage of immunosuppressive and immune-modulating medications. cytokines play an important role in the pathogenesis of ms. objective: to evaluate the effects of rapamycin on the concentrations of th1/th2/th17 serum cytokines in patients with ms. methods: six patients with relapsing remitting ms as a case group and 6 healthy indivi...

Journal: :Neurology 2021

#### Notable in Neurology This Week This issue features an article that investigates the safety of ocrelizumab people with relapsing and primary progressive multiple sclerosis; another examines whether a computer deep learning algorithm can detect MRI-negative focal cortical dysplasia. A featured Review neurologic conditions seen vaccines, including mRNA adenovirus vector coronavirus disease 2...

Journal: :International journal of molecular sciences 2016
Emanuele D'Amico Carmela Leone Francesco Patti

OBJECTIVES Data on pregnancy long-term effects on multiple sclerosis (MS) course are still controversial; whether experiencing more than one pregnancy exposes one to risk of the disability's accrual is still unknown. We investigated differences existing in terms of disability progression among women with MS (wwMS) who had one or more children after their MS onset. METHODS Monoparous and multi...

Background and Aim: Multiple sclerosis is the most common progressive neurological disease in young people and affects women several times more than men. Sexual problems are one of the most common symptoms in affected women, which have a great impact on the couple’s relationship and are often ignored. Therefore, the present study aimed to determine the effect of health-promoting multimedia educ...

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