نتایج جستجو برای: multiple antigen
تعداد نتایج: 945408 فیلتر نتایج به سال:
background: cervical cancer is one of the most common types of women’s reproductive cancers. a major risk factor for cervical cancer is exposure to a group of common sexually transmitted viruses called human papillomavirus (hpv). the over expression of hpv 16 i.e., e6 antigen in the tumors of suspected cervical cancer tissues. however e-6 antigen has hyaluronan binding protein site. methods: t...
The identification of cancer testis (CT) antigens has been an important advance in determining potential targets for cancer immunotherapy. Multiple previous studies have shown that CT antigen vaccines, using both peptides and dendritic cell vaccines, can elicit clinical and immunologic responses in several different tumors. This review details the expression of melanoma antigen family A, 1 (MAG...
Programmed cell death, or apoptosis, is well documented as a physiological means of eliminating activated lymphocytes and maintaining immune homeostasis. Apoptosis has also been implicated in the targeting of tumor cells by cytotoxic T lymphocytes and natural killer cells. One of the two primary mechanisms used in cell-mediated cytotoxicity is the Fas/FasLigand system. Activated or transformed ...
The multiple antigen peptide (MAP) approach is an effective method to chemically synthesize and deliver multiple T-cell and B-cell epitopes as the constituents of a single immunogen. Here we report on the design, chemical synthesis, and immunogenicity of three Plasmodium falciparum MAP vaccines that incorporated antigenic epitopes from the sporozoite, liver, and blood stages of the life cycle. ...
Abstract The treatment landscape of hematological malignancies has been evolving at an extremely fast pace. Hematological are diverse and distinct from solid tumors. These constitute challenges, which also unique opportunities for immunotherapy. five categories immunotherapies that have found success in the management allogeneic hematopoietic stem cell transplant, monoclonal antibodies innovati...
Abstract Immune responses to disease are complex and the only way understand such a response is consider behavior of multiple different cell types across both innate adaptive branches immune system. We developed Barcode Enabled Antigen Mapping (BEAM) technology enable easy enrichment antigen-specific cells. This fully integrated with 10x Genomics Chromium Single Cell Profiling Solution allow mu...
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