Staphylococcus aureus (S. aureus) represents an important pathogen of clinical relevance, causing a wide variety symptoms. The broad distribution multidrug-resistant strains necessarily demands new antibacterial agents for the treatment S. infections. aim this study was to assess activity plant-derived compounds, pure 4,5″-dihydroxy-anthraquinone-2-carboxylic acid (Rhein), against standard and ...

Abstract Implants have been considered the treatment of choice to replace missing teeth, unfortunately, peri-implant disease is still an unresolved issue. Contaminated implants may be decontaminated by physical debridement and chemical disinfectants; however, there a lack consensus regarding ideal techniques/agents used for decontamination. The objective our study was compare decontaminating ef...

Chemotherapy is one of the main strategies for reducing the rate of cancer progression or, in some cases, curing the tumour. Since a great number of chemotherapeutic agents are cytotoxic compounds, i. e. similarly affect normal and neoplastic cells, application of antitumour drugs is preferred in cancer management and therapy. In this study, the cytotoxicity of diversin was evaluated in 5637 ce...

This study investigated the potential of pinon shell polysaccharide (PSP) to enhance immunity against H9N2 subtype avian influenza virus (H9N2 AIV) in chickens. The effect of PSP treatment and H9N2 virus infection after PSP pretreatment were investigated by [3-(4, 5-dimethylthiazol-2-yl)-2, 3-diphenyl tetrazolium bromide] assay and analysis of major histocompatibility complex and cytokine mRNA ...

With the aim of discovering new anticancer agents, we have designed and synthesized novel α-aminophosphonate derivatives containing a 2-oxoquinoline structure using a convenient one-pot three-component method. The newly synthesized compounds were evaluated for antitumor activities against the A549 (human lung adenocarcinoma cell), HeLa (human cervical carcinoma cell), MCF-7 (human breast cancer...

Piceatannol is a naturally occurring polyphenolic stilbene found in various fruits and vegetables. It has been reported to possess pharmaceutical properties health benefit effects such as anticancer, antidiabetes, antioxidant, anti-inflammation, anti-obesity activities. Recently, Rhodomyrtus tomentosa have determined contain large amout of piceatannol. In this study, piceatannol was extracted i...

Intestinal epithelial cells (IEC) act as an important intestinal barrier whose function can be impaired upon induction by hypoxia. Although injuries are preventable milk-derived exosomal microRNAs (miRNAs), the underlying mechanism remains poorly understood. This study aimed to characterize effect of yak and cow milk–derived miRNA on IEC-6 under hypoxic conditions, explore milk relieve hypoxia ...

Objective: To investigate the antioxidant and cytotoxic activities of sulfur-containing glycine imine derivatives MCF-7 (human breast adenocarcinoma) DLD-1 (colorectal cell lines. Methods: This study examined (25-200 µM) via DPPH, metal chelating reduction methods. Furthermore activity MCF-7, MCF-12A (normal epithelial) DLD-1, CCD-18CO colon fibroblast) were with MTT (3-(4,5-Dimethylthiazol-2-y...

background: some antidepressant drugs can promote neuronal cell proliferation in vitro as well as hippocampal neurogenesis in human and animal models. furthermore, adipose tissue is an available source of adult stem cells with the ability to differentiate in to multiple lineages. therefore, human adipose-derived stem cells (hadscs) may be a suitable source for regenerative medical applications....