Investigations of memory in rats and nonhuman primates have demonstrated functional specialization within the medial temporal lobe (MTL), a set of heavily interconnected structures including the hippocampal formation and underlying entorhinal, perirhinal, and parahippocampal cortices. Most studies in humans, however, especially in patients with brain damage, suggest that the human MTL is a unit...

Based on the notion that the brain is equipped with a hierarchical organization, which embodies environmental contingencies across many time scales, this paper suggests that the medial temporal lobe (MTL)-located deep in the hierarchy-serves as a bridge connecting supra- to infra-MTL levels. Bridging the upper and lower regions of the hierarchy provides a parallel architecture that optimizes in...

Medial temporal lobe (MTL) structures may constitute a representational hierarchy, rather than a dedicated system for memory. Barense et al. (2012) show that intact memory for object features can interfere with perception of complex objects in individuals with MTL amnesia.

The importance of the medial temporal lobe to episodic memory has been recognized for decades. Recent human fMRI findings have begun to delineate the functional roles of different MTL regions, most notably the hippocampus, for the retrieval of episodic memories. Importantly, these studies have also identified a network of cortical regions--each interconnected with the MTL--that are also consist...

Metric Temporal Logic (MTL) is a widely-studied real-time extension of Linear Temporal Logic. In this paper we survey results about the complexity of the satisfiability and model checking problems for fragments of MTL with respect to different semantic models. We show that these fragments have widely differing complexities: from polynomial space to non-primitive recursive and even undecidable. ...

We present the preliminary design for a C++ template library to enable the compositional construction of matrix classes suitable for high performance numerical linear algebra computations. The library based on our interface definition — the Matrix Template Library (MTL) — is written in C++ and consists of a small number of template classes that can be composed to represent commonly used matrix ...

The MIT Microsystems Technology Laboratories (MTL) is an interdepartmental laboratory whose mission is to foster research and education in semiconductor process and device technology and in integrated circuits and systems design. MTL provides microand nanofabrication and computer-aided design (CAD) infrastructure to the entire campus. MTL has 36 core faculty members who are engaged in diverse r...

Across many cultures people conceptualize time as extending along a horizontal Mental Time Line (MTL). This spatial mapping of time has been shown to depend on experience with written text, and may also depend on other graphic conventions such as graphs and calendars. All of this information is typically acquired visually, suggesting that visual experience may play an important role in the deve...

Using functional magnetic resonance imaging, the current study explored the differential mnemonic contributions of the hippocampus and surrounding medial temporal lobe (MTL) cortices to explicit recognition memory and configural learning. Using a task that required processing of repeated and novel visuospatial contexts across multiple trials, we examined MTL activation in relation to 3 forms of...

Dual process theories of recognition memory posit that recollection and familiarity represent dissociable processes. Animal studies and human functional imaging experiments support an anatomic dissociation of these processes in the medial temporal lobes (MTL). By this hypothesis, recollection may be dependent on the hippocampus, while familiarity appears to rely on extrahippocampal MTL (ehMTL) ...