نتایج جستجو برای: mrna gene expression
تعداد نتایج: 1641040 فیلتر نتایج به سال:
Introduction: Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-2 (Nox2) is one of the predominant sources of ROS production during myocardial ischemia-reperfusion and can be induced by angiotensin II. The evidence suggests that pharmacological blockers of renin-angiotensin system can exert direct tissue effects independent of their ability to regulate blood pressure. The mechanism...
Background: One of the most growing diseases is the onset of atherosclerosis which can be started from a fetal age. As a result, the intrauterine environment plays a role at risk of spreading this disease. Changes in vascular function considered to be as an indicator for vascular disease. Effective factors on vascular function are enzyme eNOS and apoptotic regulator factors included BCL-2 an...
Objective(s):Breast cancer is an important leading cause of death from cancer. Stathmin and tau proteins are regulators of cell motility, and their overexpression is associated with the progression and bad prognosis of breast cancer. Memantine, an N-methyl-D-aspartate (NMDA) receptor antagonist, is the potential inhibitor of tau protein in neurons. This study determines the effect of memantine ...
Today, the use of oak as a replacement feed in poultry diets is well documented. However, oak contains polyphenol compounds (tannins) as antinutrient factors resulted in limited usage in the poultry rations. Generally, consumption of feeds containing tannin could affect gene expression level of immune system. Therefore, the aim of this study was to investigate the effect of different levels of ...
Background: A growing body of literature has revealed the effective role of miR-34a, as a tumor suppressor and regulator of expression of multiple targets in tumorigenesis and cancer progression. This study aimed at evaluating the potential effects of miR-34a alone or in combination with paclitaxel on breast cancer cells. Methods: After miR-34a transduction by lentiviral vectors in two MCF-7 an...
Abstract Background: Efflux systems are components of the bacterial membrane that play a role in homeostasis of the cell and extrusion of toxic compounds. Efflux pumps of the resistance nodulation cell division (RND) superfamily, confer multidrug resistance to their host when over-expressed. One of the RND efflux systems, is AdeABC which have been characterized for A. baumannii. Another pump be...
Asthenozoospermia is one of the major causes of male infertility, the motility of the sperm is decreased or absent in these men. Male infertility occurs in approximately 50% of infertile couples and among the many genetic causes of infertility, we can mention cytogenetic abnormalities, gene defects, and epigenetic factors. The aberrant mRNA expression of some genes can also impair sperm motilit...
Introduction: Ghrelin and Orexin A exert inhibitory effects on gonadotropins secretion. Aromatase is a key enzyme in the steroidogenesis pathway which converts testosterone to the estradiol. Treatment of neonatal female rats with testosterone propionate (TP) alters gonadotropin secretion patterns in the adulthood. In the present study the effects of central injection of ghrelin or orexin A o...
Background and Objective: Apoptosis plays a key role in the pathogenesis of a variety of cardiovascular diseases, especially cardiac failure. Therefore, the purpose of this study was investigating the effect of Origanum vulgare extract supplementation with and without exercise training on p53 and cytochrome c gene expression in myocardium of male rats. Materials and Methods: Nineteen three-...
abstract phosphoenolpyruvate carboxykinase, encoded by the pepck gene, plays an important role in gluconeogenesis. it also seems to be important in metabolism of nitrogenous compounds in developing seeds of legumes, including amides and ureides which are then transformed into amino acids, necessary for the synthesis of storage proteins. in this research, pepck gene expression in mrna level, in ...
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