نتایج جستجو برای: mri rat

تعداد نتایج: 379670  

Journal: :Current neurovascular research 2007
Lin Yang You-Min Guo Tai-Zhen Han Kai Meng Wen Xie

To investigate the effects of magnetic resonance image (MRI) exposure on CNS development, we examined the effects of neonatal exposure of rats to a MRI magnetic field on their performance in the Morris water maze. After birth, all litters were randomly divided into an MRI-scanning group (experimental group) comprised of 7 mother rats and their offspring, and a control group, which consisted of ...

2012
Muhammad G. Saleh Sarah-Kate Sharp Alkathafi Alhamud Bruce S. Spottiswoode Andre J. W. van der Kouwe Neil H. Davies Thomas Franz Ernesta M. Meintjes

Purpose. To evaluate whether 3T clinical MRI with a small-animal coil and gradient-echo (GE) sequence could be used to characterize long-term left ventricular remodelling (LVR) following nonreperfused myocardial infarction (MI) using semi-automatic segmentation software (SASS) in a rat model. Materials and Methods. 5 healthy rats were used to validate left ventricular mass (LVM) measured by MRI...

2014
Dapeng Li Huilin Yang Yonghui Huang Yan Wu Taicun Sun Xuefeng Li

To establish a minimally invasive rat model of lumbar intervertebral disc degeneration (IDD) to better understand the pathophysiology of the human condition. The annulus fibrosus of lumbar level 4-5 (L4-5) and L5-6 discs were punctured by 27-gauge needles using the posterior approach under C-arm fluoroscopic guidance. Magnetic resonance imaging (MRI), histological examination by hematoxylin and...

Journal: :Stroke 2012
Fabian Arnberg Johan Lundberg Michael Söderman Peter Damberg Staffan Holmin

BACKGROUND AND PURPOSE Experimental models are essential for research on ischemic stroke, the second most common cause of death worldwide. The failure of clinical trials on neuroprotective treatment may be due in part to poor animal models. To push the translation of new therapies, we describe a new rat model that captures key elements of human brain ischemia. The model includes imaging and neu...

2017
Pei Li Ruijie Zhang Qiang Zhou

OBJECTIVES Several animal studies have demonstrated the positive effects of platelet-rich plasma (PRP) on disc degeneration retardation. The present meta-analysis was to verify the efficacy of PRP in retarding disc degeneration in animal. METHODS Relevant studies were identified and evaluated according to our inclusion and exclusion criteria. The standardized mean difference (SMD) and related...

2011
Lejla Alic Joost C. Haeck Karin Bol Stefan Klein Sandra T. van Tiel Piotr A. Wielepolski Marion de Jong Wiro J. Niessen Monique Bernsen Jifke F. Veenland

BACKGROUND Magnetic resonance imaging (MRI), together with histology, is widely used to diagnose and to monitor treatment in oncology. Spatial correspondence between these modalities provides information about the ability of MRI to characterize cancerous tissue. However, registration is complicated by deformations during pathological processing, and differences in scale and information content....

2013
Aleksandra Milutinović Ruda Zorc-Pleskovič Marko Živin Andrej Vovk Igor Seša Dušan Šuput

In vivo visualization of kidney and liver damage by Magnetic Resonance Imaging (MRI) may offer an advantage when there is a need for a simple, non-invasive and rapid method for screening of the effects of potential nephrotoxic and hepatotoxic substances in chronic experiments. Here, we used MRI for monitoring chronic intoxication with microcystins (MCs) in rat. Male adult Wistar rats were treat...

2015
Christina M. Lewis Stephen A. Graves Reinier Hernandez Hector F. Valdovinos Todd E. Barnhart Weibo Cai Mary E. Meyerand Robert J. Nickles Masatoshi Suzuki

There is a growing demand for long-term in vivo stem cell imaging for assessing cell therapy techniques and guiding therapeutic decisions. This work develops the production of (52)Mn and establishes proof of concept for the use of divalent metal transporter 1 (DMT1) as a positron emission tomography (PET) and magnetic resonance imaging (MRI) reporter gene for stem cell tracking in the rat brain...

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