Background Myocardial blood flow (MBF) can be quantified from arterial input function (AIF) and myocardial output function in perfusion MRI by using tracer kinetic modeling. Fermi function constrained deconvolution has been widely used to determine MBF and myocardial perfusion reserve (MPR). However, stress MBF and MPR in healthy subjects quantified by the Fermi deconvolution approach were repo...

We design a cross-layer approach to aid in developing a cooperative solution using multi-packet reception (MPR), network coding (NC), and medium access (MAC). We construct a model for the behavior of the IEEE 802.11 MAC protocol and apply it to key small canonical topology components and their larger counterparts. The results obtained from this model match the available experimental results wit...

BACKGROUND Despite increasing clinical use, there is limited data regarding regadenoson in stress perfusion cardiovascular magnetic resonance (CMR). In particular, given its long half-life the optimal stress protocol remains unclear. Although Myocardial Perfusion Reserve (MPR) may provide additive prognostic information, current techniques for its measurement are cumbersome and challenging for ...

Enzyme or gene replacement therapy with acid α-glucosidase (GAA) has achieved only partial efficacy in Pompe disease. We evaluated the effect of adjunctive clenbuterol treatment on cation-independent mannose-6-phosphate receptor (CI-MPR)-mediated uptake and intracellular trafficking of GAA during muscle-specific GAA expression with an adeno-associated virus (AAV) vector in GAA-knockout (KO) mic...

OBJECTIVE The purpose of this study was to assess the relationship between adherence to statin therapy and LDL cholesterol goal achievement in patients with diabetes and dyslipidemia. RESEARCH DESIGN AND METHODS The records of patients being medically treated for dyslipidemia in a managed care diabetes program from January 2001 to December 2002 were used to assess LDL cholesterol goal attainm...

Seventy-six Angus steers chosen from breeding lines divergently selected for residual feed intake (RFI) were studied to quantify the relationship between RFI and the daily rate of methane production (MPR). A 70-d feeding test using a barley-based ration was conducted in which the voluntary DMI, feeding characteristics, and BW of steers were monitored. The estimated breeding value (EBV) for RFI ...

The visual-analogue scale (VAS), Likert item (rating scale), pills identification test (PIT), and medication possession ratio (MPR) provide estimates of antiretroviral therapy (ART) adherence which correlate with HIV viral suppression. These simple adherence measures are inexpensive and easy to administer; however, require validation and adjustment prior to implementation. The objective of this...

An aspartic proteinase, Mucor pusillus rennin (MPR), of filamentous fungus Mucor pusillus, is efficiently secreted from a transformant of Saccharomyces cerevisiae containing the intact MPR gene. To test the usefulness of the MPR leader peptide in secretion of heterologous proteins from yeast cells, several plasmids encoding the fusion proteins composed of different parts of the NH2-terminal reg...