نتایج جستجو برای: mpk
تعداد نتایج: 187 فیلتر نتایج به سال:
Programmed cell death (PCD) is the physiological death of a cell mediated by an intracellular suicide program. Although key components of the PCD execution pathway have been identified, how PCD is regulated during development is poorly understood. Here, we report that the epidermal growth factor (EGF)-like ligand LIN-3 acts as an extrinsic signal to promote the death of specific cells in Caenor...
Emerging evidences exhibit that mitogen-activated protein kinase (MAPK/MPK) signaling pathways are connected with many aspects of plant development. The complexity of MAPK cascades raises challenges not only to identify the MAPK module in planta but also to define the specific role of an individual module. So far, our knowledge of MAPK signaling has been largely restricted to a small subset of ...
Kager (2012), Martínez-Paricio & Kager (2013), and Martínez-Paricio (2013) — collectively MPK — propose the layered feet ((σσ)σ) and (σ(σσ)) to account for a variety of phenomena, including stress windows, mixed binary and ternary alternations, and extrametricality. Although many metrical theories do not accommodate left-edge extrametricality, they use constraints that are almost entirely symme...
Spatiotemporal-specific cell proliferation and cell differentiation are critical to the formation of normal tissues, organs, and organisms. The highly coordinated cell differentiation and proliferation events illustrate the importance of cell-cell communication during growth and development. In Arabidopsis thaliana, ERECTA (ER), a receptor-like protein kinase, plays important roles in promoting...
Reversible phosphorylation is a key mechanism for regulating protein function. Thus it is of high interest to know which kinase can phosphorylate which proteins. Comprehensive information about phosphorylation sites in Arabidopsis proteins is hosted within the PhosPhAt database (http://phosphat.mpimp-golm.mpg.de). However, our knowledge of the kinases that phosphorylate those sites is dispersed...
Microprocessor prosthetic knees (MPKs) have advanced technologically, offering new features to decrease impairment and activity limitations for persons with transfemoral amputation (TFA). The Genium knee is functionally untested, and functional differences between it and intact knees are unknown. This study sought to determine whether Genium use improves functional performance compared with the...
Given a graph with edge costs, the power of a node is the maximum cost of an edge leaving it, and the power of a graph is the sum of the powers of its nodes. Motivated by applications in wireless networks, we consider several fundamental undirected network design problems under the power minimization criteria. The Minimum-Power Edge-Cover (MPEC) problem is: given a graph G = (V, E) with edge co...
Under replete growth conditions, abundant nutrient uptake leads to the systemic activation of insulin/IGF-1 signalling (IIS) and the promotion of stem cell growth/proliferation. Activated IIS can stimulate the ERK/MAPK pathway, the activation of which also supports optimal stem cell proliferation in various systems. Stem cell proliferation rates can further be locally refined to meet the reside...
When MPI began to take form as a rather high-level interface with extensive features, it became somewhat less attractive to some benchmarkers and tool builders who required a very efficient low-level portable interface and did not need extensive features targeted toward application development. As a result, the Message Passing Kernel (MPK) project began at NAS. The name changed to the Cooperati...
Antibody-drug conjugates (ADC) represent a promising therapeutic modality for managing cancer. Here, we report a novel humanized ADC that targets the tetraspanin-like protein TM4SF1. TM4SF1 is highly expressed on the plasma membranes of many human cancer cells and also on the endothelial cells lining tumor blood vessels. TM4SF1 is internalized upon interaction with antibodies. We hypothesized t...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید