During sex differentiation, androgens are essential for development of the male genital tract. The Wolffian duct is an androgen-sensitive target tissue that develops into the epididymis, vas deferens, and seminal vesicle. The present study aimed to identify androgen-regulated proteins that are involved in development of Wolffian duct-derived structures. We have used male mouse embryos transgeni...

Delivering an injection correctly into the small diamater lumen of a tubular biological structure placed under the skin and not visible to the eye presents difficulties in medical practice. Suitable assist devices are currently not available. A new concept has been formulated to combine four modes of nonradiological imaging: scanning electrical impedance plethysmography; ultrasound; transillumi...

CFTR mutations enhance susceptibility for idiopathic chronic pancreatitis (ICP) and congenital bilateral absence of the vas deferens (CBAVD); however, it is unknown why CFTR heterozygotes are at increased disease risk. We recently showed that common CFTR variants are associated with aberrantly spliced transcripts. Here, we genotyped for common CFTR variants and tested for associations in two IC...