Basal cell carcinoma (BCC) is the most common human malignancy. Recent advances in our understanding of the critical biologic pathways implicated in the development and progression of BCC have led to the development of the first molecular targeted therapy for this disease. The hedgehog pathway is mutated in virtually all patients with BCC and recent trials with vismodegib, an inhibitor of this ...

In this paper, we thoroughly study a trilinear interpolation scheme previously proposed for the Body-Centered Cubic (BCC) lattice. We think that, up to now, this technique has not received the attention that it deserves. By a frequency-domain analysis we show that it can isotropically suppress those aliasing spectra that contribute most to the postaliasing effect. Furthermore, we present an eff...

Basal cell carcinoma (BCC) is one of the most common skin cancers. In this paper, we present an automatic BCC detector based on confocal Raman spectroscopy. Maximum a posterior (MAP) classifier was adopted as a detector using features obtained with principal component analysis (PCA). Fisher measure filtering (FMF) is proposed to enhance the performance of BCC detector. Since FMF eliminates non-...

This paper surveys recently developed analytical methods for studying the sensitivity of DEA results to variations in the data. The focus is on the stability of classification of DMUs (Decision Making Units) into efficient and inefficient performers. Early work on this topic concentrated on developing solution methods and algorithms for conducting such analyses after it was noted that standard ...

The DMU-package for Analyzing Multivariate Mixed Models has been developed over a period of more than 25 years. This paper gives an overview of new features and the recent developments around the DMU-package, including: Genomic prediction (SNPBLUP, G-BLUP and “One-Step”), Genome-wide association studies, Survival models and double hierarchical generalized linear mixed models.

In this paper we first (trivially) show that data envelopment analysis can be viewed as maximising the sum of the efficiencies of the decision-making units (DMU's) in the organisation. Building upon this we present nonlinear models for: (a) allocating fixed costs to DMU's and (b) allocating resources to DMU's. Simultaneous to allocating resources output targets are also decided for each DMU. Nu...

Data envelopment analysis (DEA), as originally proposed, is a methodology for evaluating the relative efficiencies of a set of homogeneous decision-making units (DMUs) in the sense that each uses the same input and output measures (in varying amounts from one DMU to another). In some situations, however, the assumption of homogeneity among DMUs may not apply. As an example, consider the case wh...

The aim of this paper is to estimate the efficiency of the Slovak commercial banks employing the Data Envelopment Analysis (DEA) window analysis approach during the period 20032012. The research is based on unbalanced panel data of the Slovak commercial banks. Undesirable output was included into analysis of banking efficiency. It was found that most efficient banks were Postovabanka, UniCredit...