A series of 1-(2-diphenylphosphinoferrocenyl)ethyl-3-substituted imidazolium iodides [3-substituent = methyl (1a); isopropyl (1b); tert-butyl (1c); 1-adenosyl (1d); cyclohexyl (1e); 2,6-dimethylphenyl (1f); 2,4,6-trimethylphenyl (1g); 2,6-diisopropylphenyl (1h)] have been prepared and evaluated as ligands in the palladium-catalyzed aminations of aryl halides with various amines. The scope of th...

Catalytic osmylation of cis and trans 2-cyclohexene-cyclohexanol (1a) and (1b) are carried out in the presence of N-methyl morpholine-N-oxide. Under the same conditions, only the cis isomer reacted, leading to triol (3). The steric hindrance of the equatorial OH group probably prevents the trans isomer from entering into such reaction. Triol (3) was also obtained from the reduction of the d...

Four new complexes of the type [LCo ((DO)(DOH) pn) Cl] PF , where (DO) (DOH) pn = N , N '- propanediylbis (2, 3-butanedione2-imine3-oxirne)a nd L =morpholine (mrpln) (I), benzylamine (bzlan) (II), piperidine (pprdn)(III) and pyrrolidine (prldn) (IV) have been synthesized and characterized by elemental analyses and spectroscopic methods. Approximate values of the angular-overlap parameter, ?, ...

Due to their high carcinogenicity, the control of nitrosamines, a group of disinfection by-products (DBPs), is an important issue for drinking water supplies. In this study, a method using ultra-performance liquid chromatography-electrospray ionization tandem mass spectrometry was improved for simultaneously analyzing nine nitrosamines in source water and finished water samples of twelve drinki...

A novel arotinoid, 4-((2-(p-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl- 2-naphthyl)propenyl]phenoxy))ethyl))-morpholine, was tested in rats bearing established chemically induced mammary tumors. At a dose of 0.35 mmol/kg/day of 4-((2-(p-[(E)-2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2- naphthyl)propenyl]phenoxy)ethyl))-morpholine, decreased tumor growth was seen after 2 weeks. By weeks 4 an...

Synthesizing azoles from ortho-substituted anilines, CO2 and H2 has proved difficult due to the low nucleophilicity of which hinders their N-formylation, i.e., first step reaction. Herein, we demonstrate that R3SnX Lewis acids (LA), N-methylmorpholine (NMM) or DBU polyethyleneimine (PEI) N-formylmorpholine efficiently catalyse synthesis benzimidazole other by reductive coupling nucleophilic ami...

The paper present results of studies the two-stage preparation C10-C12 tricyclic vicinal amino alcohols from partially hydrogenated condensation products cyclopentadiene and cyclohexa-1,3-diene, by epoxidizing them with hydrogen peroxide in presence cobalt-containing polyoxomolybdate, followed aminolysis oxidate diethylamine, morpholine, or piperidine. structure synthesized compounds was confir...