BACKGROUND Regardless the progress in perioperative care postoperative cognitive decline (PCD) has been accepted unequivocally as a significant and frequent complication of surgery in older patients. The aim of this study was to evaluate the incidence of postoperative cognitive decline and its influence on quality of life three months after surgery. METHODS Observational, prospective study in...

OBJECTIVE Cognitive deficits are common after aneurysmal subarachnoid haemorrhage (aSAH), and clinical evaluation is important for their management. Our hypothesis was that the Montreal Cognitive Assessment (MoCa) is superior to the Mini-Mental State Examination (MMSE) in screening for cognitive domain deficit in aSAH patients. METHODS We carried out a prospective observational and diagnostic...

BACKGROUND AND PURPOSE Cognitive function is often ignored in stroke research trials. The brief Montreal Cognitive Assessment (MoCA) may be sensitive to stroke-related cognitive deficits. METHODS We evaluated the feasibility of administering the MoCA at 3 months in a large stroke trial (A Very Early Rehabilitation Trial [AVERT]). RESULTS Data (blinded to intervention group) are presented fo...

M ore than 40% of stroke survivors are found with cog-nitive impairment (poststroke cognitive impairment [PSCI]) sometime after the event. 1 Almost two thirds of these patients are affected by mild cognitive impairment (MCI). 2 A meta-analysis showed that 10% of patients had dementia before first stroke, 10% developed dementia soon after first stroke, and more than a third had dementia after re...

PURPOSE Cognitive screening upon hospital admission can provide important information about the patient's ability to process information during the inpatient stay. The Clock-in-the-Box (CIB) is a rapidly administered cognitive screening measure which has been previously validated with cognitive screening and neuropsychological assessments. The purpose of this study is to demonstrate the predict...

PURPOSE To determine in a large multiethnic cohort the cardiovascular and genetic risk factors associated with smaller volume in the hippocampus, precuneus, and posterior cingulate, and their association with preclinical deficits in cognitive performance in patients younger and older than 50 years. MATERIALS AND METHODS The institutional review board approved the study and all participants pr...