Although mimics of human tumor antigens are effective immunogens to overcome host unresponsiveness to the nominal antigen, the structural basis of this mimicry remains poorly defined. Therefore, in this study we have characterized the structural basis of the human high molecular weight-melanoma-associated antigen (HMW-MAA) mimicry by the mouse anti-idiotypic (anti-id) monoclonal antibody (mAb) ...

gut microbiota is formed by ten of trillions of microorganisms with at least 1000 different species of known bacteria. one - third of an individual gut microbiota is common to most people, while two - thirds are specific to him. growing amount of evidence indicates that gut microbiota characteristics may play an important role in mental dysfunctions. molecular mimicry between several key neurop...

The central question in communication theory is whether communication is reliable, and if so, which mechanisms select for reliability. The primary approach in the past has been to attribute reliability to strategic costs associated with signalling as predicted by the handicap principle. Yet, reliability can arise through other mechanisms, such as signal verification; but the theoretical underst...

The ability of mimicry to signal affiliation to, and elicit affiliation from, the mimicked person has generated great interest, but no definitive account of these phenomena has emerged. While affiliation is often cited as the driving force behind mimicry, ...