The technology of DNA self-assembly has played an important role in the field of DNA computing and nanotechnology. Many small-scaled NP complete problems can be solved by self-assembly model. In this paper, we based on the addition of two numbers, and proposed the addition of two matrices of DNA Tile self-assembly model. The algorithm can be applied to add two elements in the corresponding posi...

In this paper, the problem of lot sizing, scheduling and delivery of several items in a two-stage supply chain over a finite planning horizon is studied. Single supplier via a flexible flow line production system (FFL), produces several items and delivers them directly to an assembly facility. Based on basic period (BP) strategy, a new mixed zero-one nonlinear programming model has been develop...

In this paper a mixed-model assembly-line sequencing problem with the goal of minimizing work overload is addressed. We consider time windows in work stations of the assembly line (closed stations). Different versions of a product to be assembled in the line (e.g. automotive industry), which require different processing time according to the work required in each work station are considered. In...

background : the development of chemoresistance represents a major obstacle in the successful treatment of cancers such as non-hodgkin’s lymphoma (nhl). with the recognition of important roles for both p53 and its more recently described paralog p73 in mediating the activity of anti-cancer drugs, there has been increasing recognition that cellular resistance to anthracyclines could and does a...

This paper presents our work on the application of virtualreality simulation to the design of a production line for a mechanically-assembled product. The development of this simulation was undertaken as a part of the Manufacturing Simulation and Visualization Program at the National Institute of Standards and Technology in Gaithersburg, MD. The major research problem is the partitioning and ana...

Integration of product design and operations could potentially enhance the ability of manufacturers to provide large variety in the product line while keeping their operations competitive. In this paper, we present an integrated model that provides insight on how manufacturers could design their products in order to delay diierentiation during operations. Our integrated model consists of two su...

This paper considers the economic lot and delivery scheduling problem in a two-echelon supply chains, where a single supplier produces multiple components on a flexible flow line (FFL) and delivers them directly to an assembly facility (AF). The objective is to determine a cyclic schedule that minimizes the sum of transportation, setup and inventory holding costs per unit time without shortage....