Background and Purpose—Transcranial color-coded duplex sonography (TCCS) allows bedside imaging of intracranial hemodynamics and parenchymal structures. It provides reliable information regarding midline shift (MLS) in space-occupying hemispheric stroke. We studied the value of MLS measurement to predict fatal outcome at different time points after stroke onset. Methods—Forty-two patients with ...

We hypothesized that tissue-resident macrophages in familial amyloid polyneuropathy (FAP) patients will exhibit qualitative or quantitative abnormalities, that may accelerate transthyretin (TTR)-derived amyloid deposition. To evaluate this, we examined the number and subset of tissue-resident macrophages in heart tissue from amyloid-deposited FAP and control patients. In both FAP and control pa...

A multilingual, colored-letter synesthete professor (MLS), 9 nonsynesthete multilingual professors and 4 nonsynesthete art professors learned 30 names of individuals (first and last name pairs) in three trials. They recalled the names after each trial and six months later, as well as performed cued recall trials initially and after six months. As hypothesized, MLS recalled significantly more na...

In a recent study, we discovered that many single load/store operations in embedded applications can be parallelized and thus encoded simultaneously in a single-instruction multiple-data instruction, called the multiple load/store (MLS) instruction. In this work, we investigate the problem of utilizing MLS instructions to produce optimized machine code, and propose an effective approach to the ...

In a panel of large Caucasian pedigrees, we genotyped markers in eight chromosomal regions previously reported as supporting linkage with type 2 diabetes. We previously reported significant linkage on chromosome 20q (maximum logarithm of odds score [MLS] = 2.79) in this panel. In the present analysis, candidate regions on 1q, 2q, 3q, 5q, 9q, and 10q yielded little evidence for linkage; a region...

The Maximum Likelihood Set (MLS) was recently introduced in [1] as an effective, parameter-free technique for estimating a probability mass function (pmf) from sparse data. The MLS contains all pmfs that assign merely a higher likelihood to the observed counts than to any other set of counts, for the same sample size. In this paper, the MLS is extended to the case of conditional density estimat...

Stratospheric O3 profiles obtained by the satellite limb sounders Aura/MLS, ENVISAT/MIPAS, ENVISAT/GOMOS, SAGE-II, SAGE-III, UARS/HALOE are compared to coincident O3 profiles of the ground-based microwave radiometer SOMORA in Switzerland. Data from the various measurement techniques are within 10% at altitudes below 45 km. At altitudes 45–60 km, the relative O3 differences are within a range of...

Elimination of potentially self-reactive T lymphocytes during their maturation in the thymus has been shown to be a major mechanism in accomplishing self-tolerance. Previous reports demonstrated that clonal deletion of self-Mls-l a -specific V,36+ T lymphocytes is controlled by a radiosensitive I-E+ thymic component. Irradiation chimeras reconstituted with I-E bone marrow showed substantial num...

The autoimmune thyroid diseases (AITDs), comprising Graves' disease (GD) and Hashimoto's thyroiditis (HT), appear to develop as a result of a complex interaction between predisposing genes and environmental triggers. The goals of the present study were to identify the susceptibility loci for GD and HT and to study the relationships between them. We performed a whole genome linkage study on a da...

BACKGROUND Airway management is critical in patients with cervical spondylosis, a population with a high incidence of difficult airway. Intubation with Shikani Optical Stylet (SOS) has become increasingly popular in difficult airway. We compared the effects of intubation with SOS versus Macintosh laryngoscope (MLS) in patients undergoing surgery for cervical spondylosis. METHODS A total of 27...