نتایج جستجو برای: mirna and multiple sclerosis
تعداد نتایج: 16931715 فیلتر نتایج به سال:
within communicative, interactive, and learner-centered framework of language teaching and learning, students need to learn four skills of listening, speaking, reading, and writing for their educational success. but of all the language skills, reading enjoys a paramount significance in so many second or foreign language academic contexts. in spite of its importance, language learners still have...
: بیماری ms (multiple sclerosis)، شایع ترین بیماری التهابی دمیلینیه کننده سیستم عصبی مرکزی است که باعث تخریب پوشش محافظ اعصابی (میلین)، داخل و اطراف مغز و نخاع می شود. از جمله مشکلات حاصل از این بیماری اختلالات بینایی، حرکتی، حسی، تعادلی، کیفیت خواب است. تاکنون درمان قطعی این بیماری پیدا نشده، ضمنأ مصرف اکثر داروهای شیمیایی نیز همراه با عوارض جانبی برای بیماران مبتلا می باشد. بنا براین مطالعه ب...
Interest in RNA dysfunction in amyotrophic lateral sclerosis (ALS) recently aroused upon discovering causative mutations in RNA-binding protein genes. Here, we show that extensive down-regulation of miRNA levels is a common molecular denominator for multiple forms of human ALS. We further demonstrate that pathogenic ALS-causing mutations are sufficient to inhibit miRNA biogenesis at the Dicing ...
the present study investigated construct equivalence of multiple choice (mc) and constructed response (cr) item types across stem and content equivalent mc and cr items (item type ‘a’), non-stem-equivalent but content equivalent mc and cr items (item type ‘b’), and non-stem and non-content equivalent mc and cr items (item type ‘c’). one hundred seventy english-major undergraduates completed mc ...
how to cite this article: inaloo s, haghbin s, moradi m, dashti h, safari n. acquired cns demyelinating syndrome in children referred to shiraz pediatric neurology ward. iran j child neurol. 2014 spring; 8(2):18-23. objective incidence of cns acquired demyelinating syndrome (ads), especially multiple sclerosis (ms) in children, appears to be on the rise worldwide. the objective of this study wa...
abstract aim and background: the purpose of the present study was to examine the psychometric properties of multiple sclerosis self-efficacy scale (msss) in a sample population of iranian patients. methods and materials: this research is a descriptive-correlational study with a population of patients afflicted with ms from north khorasan and hamedan provinces. a number of 120 patients, who had ...
patients and methods this cross-sectional study was performed on 1202 ms patients in farshchian hospital, hamadan, in 2013. all patients were diagnosed with definite ms. a questionnaire was used to gather information; demographic characteristics, medical history, signs and symptoms at onset, course of disease, relatives with ms, and degree and type of relationship were recorded. conclusions the...
results the results showed that there was no statistical significant difference in distribution of genotype (aa, ac and cc) and allele (a and c) frequencies between ms patients and healthy controls (p = 0.901 and p = 0.728, respectively). conclusions in conclusion, it appears that the c424c/a polymorphism within the il-25 gene has no significant relationship with ms, and this polymorphism is pr...
optic neuritis occurs in young patients, most often females, and presents as subacute monocular visual loss. periocular pain, particularly with eye movement occurs in the majority of cases. the retrobulbar form occurs in 65% of cases and is associated with normal optic disc appearance at onset. the central visual field is usually affected and an rapd and dyschromatopsia are present. brain magne...
multiple sclerosis (ms) is an inflammatory disease of the central nervous system (cns). inflammation caused by immune cells destroy the myelin and then axon. cns failure to complete repair results in permanent disabilities. some types of stem cells have special potentials to repair these injuries and even cure ms. neural crest stem cells with a mutual origin with cns and the ability of differen...
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