The neuroscience of flavor perception is becoming increasingly important to understand abnormal feeding behaviors and associated chronic diseases such as obesity. Yet, flavor research has mainly depended on human subjects due to the lack of an animal model. A crucial step towards establishing an animal model of flavor research is to determine whether the animal uses the retronasal mode of olfac...

Ribosome biogenesis in eukaryotes requires the participation of a large number of ribosome assembly factors. The highly conserved eukaryotic nucleolar protein Nep1 has an essential but unknown function in 18S rRNA processing and ribosome biogenesis. In Saccharomyces cerevisiae the malfunction of a temperature-sensitive Nep1 protein (nep1-1(ts)) was suppressed by the addition of S-adenosylmethio...

The proteins in DUF358 family are all bacterial proteins, which are ∼200 amino acids long with unknown function. Bioinformatics analysis suggests that these proteins contain several conserved arginines and aspartates that might adopt SPOUT-class fold. Here we report crystal structure of Methanocaldococcus jannaschii DUF358/Mj1640 in complex with S-adenosyl-L-methionine (SAM) at 1.4 Å resolution...

Simple harmonic motion of two moving tines can induce a relative motion between two adjacent stationary lines. There is both a maximum and minimum stimulus amplitude within which this motion can be seen and this depends on frequency. For a wide range of low frequencies the lower amplitude limit for induced motion is inversely proportional to frequency, suggesting that the phenomenon requires a ...

Mobile sensors cover more area over a period of time than same number of stationary sensors. However, the quality of coverage achieved by mobile sensors depends on the velocity, mobility pattern, number of mobile sensors deployed and the dynamics of the phenomena being sensed. The gains attained by mobile sensors over static sensors and the optimal motion strategies for mobile sensors are not w...

Mobile sensors cover more area over a period of time than same number of stationary sensors. However, the quality of coverage achieved by mobile sensors depends on the velocity, mobility pattern, number of mobile sensors deployed and the dynamics of the phenomena being sensed. The gains attained by mobile sensors over static sensors and the optimal motion strategies for mobile sensors are not w...

Mobile sensors cover more area over a fixed period of time than the same number of stationary sensors. However, the quality ofcoverage achieved by mobile sensors depends on the velocity, mobility pattern, number of mobile sensors deployed and the dynamicsof the phenomenon being sensed. The gains attained by mobile sensors over static sensors and the optimal motion strategies formobi...