نتایج جستجو برای: miltefosine
تعداد نتایج: 701 فیلتر نتایج به سال:
Human colon cancer is the third most common and the fourth most frequent cause of cancer deaths worldwide [1]. The marketing chemotherapeutic drugs for the treatment of colon related cancer are Carboplatin, Levamisole, Miltefosine, Semustine and Floxuridine (Chart 1). The chart displays that most of the drugs are organic compounds. Among these, only Carboplatin is a metal based anticancer drug ...
We describe here two cases, one male and one female, both age 40 years, with visceral leishmaniasis and HIV-1 co-infection. The female patient had features of Koch's abdomen. The male patient had features of tuberculous lymphadenitis and bilateral pleural effusion more marked on the right side. Both were treated with highly active antiretroviral therapy, antituberculous drugs, antibiotics, anti...
Naegleria fowleri is a thermophilic, free-living ameba that causes primary amebic meningoencephalitis. The infections are nearly always fatal. We present the third well-documented survivor of this infection in North America. The patient's survival most likely resulted from a variety of factors: early identification and treatment, use of a combination of antimicrobial agents (including miltefosi...
A series of 9 quinolines and 18 styrylquinolines was evaluated for the drugs' in vitro antileishmanial activities and cytotoxicities. The 7-aroylstyrylquinoline scaffold appeared to be the most promising one, with the most interesting compound, no. 35, exhibiting a 50% inhibitory concentration (IC(50)) of 1.2 μM and a selectivity index value of 121.5. Compound 35 was 10-fold and 8-fold more act...
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