نتایج جستجو برای: mild hypothermia therapy glutathione gsh

تعداد نتایج: 806898  

Journal: :American journal of physiology. Renal physiology 2002
Edmund Purucker Hanns-Ulrich Marschall Andreas Geier Carsten Gartung Siegfried Matern

Hepatic synthesis and plasma levels of glutathione are markedly decreased in chronic liver disease. Because glutathione turnover is highest in kidneys, we examined whether changes in kidney glutathione occur in chronic cholestasis and whether they are related to kidney dysfunction in liver disease. Kidney and plasma GSH and GSSG were measured 1) in bile duct-ligated (BDL) rats; 2) in healthy ra...

2014
Andreas M. Lisewski

Membrane glutathione S-transferases from the class of membrane-associated proteins in eicosanoid and glutathione metabolism (MAPEG) form a superfamily of detoxification enzymes that catalyze the conjugation of reduced glutathione (GSH) to a broad spectrum of xenobiotics and hydrophobic electrophiles. Evolutionarily unrelated to the cytosolic glutathione S-transferases, they are found across bac...

2015
Liang Tang Weiwei Wang Wenlong Zhou Kai Cheng Yan Yang Minzhi Liu Kedi Cheng Wei Wang

BACKGROUND Glutathione (GSH), a pivotal non-protein thiol, can be biosynthesized through three pathways in different organisms: (1) two consecutive enzymatic reactions catalyzed by γ-glutamylcysteine synthetase (Gsh1 or GshA) and glutathione synthetase (Gsh2 or GshB); (2) a bifunctional γ-glutamylcysteine synthetase/glutathione synthetase (GshF); (3) an alternative condensation of γ-glutamyl ph...

Kanhiya Mahour, Prabhu N Saxena,

Introduction: The fate of xenobiotics that is present, increasing day by day. The increasing fates altered or inhibit the metabolic activities like detoxification and biotransformation. Methods: The present study highlights this slow biotransformation and detoxification on the basis of specific enzymes which have a say in assessment of mercuric chloride toxicity and modulation by Panax ginse...

Journal: :Indian journal of experimental biology 2002
V Kannan P N Raju

Protection of nitrogenase against oxygen inactivation in diazotrophs involves numerous strategies. Glutathione is known to play an important role in scavenging oxyradicals in many living systems. The involvement of glutathione (reduced) (GSH), glutathione peroxidase (GPX) and glutathione reductase (GR) in the protection of nitrogenase in free living diazotrophs is reported here for the first ti...

Journal: : 2021

Earlier works have revealed increased generation of reactive oxygen species (ROS) and decreased antioxidant levels in type 1 diabetes mellitus (T1DM). The current study aimed to investigate the effect mixed insulin therapy on oxidative stress status patients with T1DM. This involved 75 participants who were divided into three groups: 20 healthy subjects as a control, 25 newly diagnosed T1DM (wi...

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