objective(s): the study aimed to investigate the effects of resveratrol on colorectal cancer hct116 cells, including cell viability, apoptosis, and migration, and the partial mechanisms focused on hedgehog/gli-1 signaling pathways. materials and methods: we chose the appropriate time and concentration of recombinant human sonic hedgehog (shh) stimulation by cell viability. the proportion of cel...

one of the key issues of migration concerns women’s migration. this article, examines the conditions of skilled immigrant women in ehran. qualitative method is used to collect the necessary data for this tudy. the research also conducts in-depth interview with 25 immigrate women residing in tehran. the results of the research show that migration decisions depend on multiple factors including la...

We present an overview of algorithms and data structures for dynamic re nement/coarsening (adaptation) of unstructured FE meshes on loosely coupled parallel processors. We describe a) a parallel adaptation algorithm, b) an online parallel repartitioning algorithm based on mesh adaptation histories, c) an algorithm for the migration of mesh elements between processors, and d) an integrated objec...

The article presents the results of studying mineralogical and geochemical features coals clay interlayers Shubarkol deposit. There were analyzed 71 samples layers 49 coal using instrumental neutron activation analysis (INAA), powder X-ray diffractometry, scanning electron microscopy. A comprehensive characteristics their enclosing was carried out. variety criteria made it possible to establish...

Migration of Virtual Machine (VM) is a critical challenge in cloud computing. The process to move VMs or applications from one Physical Machine (PM) to another is known as VM migration. In VM migration several issues should be considered. One of the major issues in VM migration problem is selecting an appropriate PM as a destination for a migrating VM. To face this issue, several approaches are...

Hydroxymethylglutaryl coenzyme A reductase (HMGCoAR) is required for isoprenoid and cholesterol biosynthesis. In Drosophila, reduced HMGCoAR activity results in germ cell migration defects. We show that pharmacological HMGCoAR inhibition alters zebrafish development and germ cell migration. Embryos treated with atorvastatin (Lipitor) exhibited germ cell migration defects and mild morphologic ab...

Traumatic brain injury (TBI) is one of the main causes of mortality and morbidity worldwide. Despite extensive investigations over the past few decades, no effective therapies exist to improve the brain function in patients with TBI. Neural tissue engineering is an attractive therapeutic approach to restore the brain structure and function of damaged tissue. Bioactive motif of Stromal cell-deri...