BACKGROUND Reconstruction of the bones of the skull is a complex procedure and represents a challenge for the surgical team. It is generally performed in patients who have loss of the cranial vault secondary to chronic infection or uncontrolled osteoradionecrosis, indicating a greater chance of failure or rejection of the materials used for repair of the defect. Selection of material to replace...

Digital and virtual heritage is often associated with the recreation of lost artefacts and architecture; however, we can also investigate works that were not completed, using digital tools and techniques. Here we explore physical evidence of a fourteenthcentury Gothic vault located in the north transept of St Mary’s church in Nantwich, Cheshire, using existing springer stones that are built int...

Hypothesis / aims of study Despite increase in popularity of uterus preserving techniques, vaginal hysterectomy is still a common option in the surgical treatment of uterine prolapse. However, in pelvic organ prolapse (POP) special attention has to be paid to a sufficient suspension of the vaginal vault in order to prevent recurrence of descent and to protect possibly additional repair of the v...

In the present study, we analysed exact, laser-scanned geometry of apse vault catholic church Andocs. The written sources about this are very limited, however, point cloud-based research could provide new details history building, along with formerly used building techniques. For analysis, worked based on our three-step analysis process, established for net vaults. During studying rib system, r...

The aim of this study was to assess whether pole vaulters interacted differently with the pole during normal and perturbed approach phase conditions. Six national and international level athletes performed nine jumps, which were recorded and analysed. Pole vaulters were found to produce different coordination patterns when interacting with the pole during normal and perturbed approach phase con...

dialysis-cryoprotected crystals were flash-cooled [1], using a nitrogen stream at about 105K. Using our in-house X-ray equipment for the vault crystals, we can observe diffraction strength, but we cannot collect diffraction data. In-house, the best of the C2 form crystals resulted in articulated but unresolved diffraction lunes. Only a few percent of the tested vault crystals have produced usea...

BACKGROUND The purpose of this study was to identify factors related to the unexpected vault in V4c implantable collamer lens (ICL; STAAR Surgical) implantation. METHODS V4c ICLs were implanted in 43 eyes of 43 patients for the correction of myopia. The implanted V4c ICL sizes were determined individually with our previous V4 ICL sizing nomogram based on the sulcus-to-sulcus diameter (STS), a...

BACKGROUND Based on our preclinical findings, we are assessing the efficacy of intratumoral injection of dendritic cells (DC) transduced with an adenoviral vector expressing the secondary lymphoid chemokine (CCL21) gene (Ad-CCL21-DC) in a phase I trial in advanced non-small cell lung cancer (NSCLC). While this approach shows immune enhancement, the preparation of autologous DC for CCL21 genetic...