The fast and progressive growth of the biotechnology and pharmaceutical fields forces the development of new and powerful sensing techniques for process optimization and detection of biomolecules at very low concentrations. During the last years, the simplest MEMS structures, i.e. microcantilevers, have become an emerging and promising technology for biosensing applications, due to their small ...

Intrinsic localized mode (ILM) is spatially localized and temporally periodic oscillation in nonlinear coupled oscillators. We numerically investigate the dynamical stability of ILMs in a microcantilever array, in which ILMs were experimentally observed by M. Sato et al. It is found that the stability change of ILMs is due to the ratio in nonlinear potentials. This phenomenon also occurs in the...

A label-free electrochemical nucleic acid aptasensor for the detection of methamphetamine (MA) by the immobilization of thiolated self-assembled DNA sequences on a gold nanoparticles-chitosan modified electrode is constructed. When MA was complexed specifically to the aptamer, the configuration of the nucleic acid aptamer switched to a locked structure and the interface of the biosensor changed...

At the microscale, cantilever vibrations depend not only on the microstructure’s properties and geometry but also on the properties of the surrounding medium. In fact, when a microcantilever vibrates in a fluid, the fluid offers resistance to the motion of the beam. The study of the influence of the hydrodynamic force on the microcantilever’s vibrational spectrum can be used to either (1) optim...

This paper presents the dynamic behavior of microcantilever-based microresonators and compares their steady state behavior for polarized and nonpolarized systems at different levels of nonlinearities. A microcantilever, equipped with a time-varying capacitor, makes the microresonator system. The capacitor is activated by a constant polarization voltage, and an alternative actuating voltage. The...

We outline the application of modulated–demodulated control to the quality (Q) factor control of an atomic force microscope microcantilever. We review the modulated–demodulated control technique, emphasize its linear time invariant nature and develop state space representations of the controller for design and analysis. The modulated–demodulated controller can be configured as both positive pos...

Cantilever magnetometry is a measurement technique used to study magnetic nanoparticles. With decreasing sample size, the signal strength is significantly reduced, requiring advances of the technique. Ultrathin and slender cantilevers can address this challenge but lead to increased complexity of detection. We present an approach based on the co-resonant coupling of a micro- and a nanometer-siz...