نتایج جستجو برای: microbial etiology
تعداد نتایج: 163628 فیلتر نتایج به سال:
The establishment of a biorepository with linkage to clinical and epidemiologic data will provide an invaluable resource for cancer research, including studies of cancer etiology, progression, and prognosis, as well as development of biomarkers for early detection. Developing an infrastructure for a biorepository linked to clinical, pathologic, and epidemiologic data requires significant effort...
BACKGROUND Bacteria have long been recognized as the primary etiology for pulpal and periapical lesions, which necessitates the elimination of bacteria from the root canal system. In primary teeth, irrigation and debridement is the main protocol required to disinfect the canal. Biomechanical preparation cannot be vigorously done on the primary teeth due to anatomical barrier such as thin and fl...
Background: Cholera, an acute diarrhoeal disease caused by Vibrio cholerae still ranks high in the etiology of diarrhoeal diseases in several parts of India. Aim:To study the characteristics and anti-microbial resistance pattern of the Vibrio choleraestrains isolated in our hospital. Methods: Over a 2 year period, stool samples from clinically suspected cholera cases were screened and the isola...
Understanding etiology of autoimmune diseases has been a great challenge for designing drugs and vaccines. The pathophysiology of many autoimmune diseases may be attributed to molecular mimicry provoked by microbes. Molecular mimicry hypothesizes that a sequence homology between foreign and self-peptides leads to cross-activation of autoreactive T cells. Different microbial proteins are implica...
Crohn’s disease (CD) is a disorder of the immune system leading to persistent inflammation and ulceration that may occur anywhere in the gastrointestinal tract, from mouth to anus. The etiology of CD is unknown but the disease is believed to manifest from a combination of factors which include genetic predisposition, immune dysregulation and environmental triggers. The interplay of these factor...
PURPOSE Procalcitonin has proven to be a sensitive inflammatory marker in non-neutropenic patients. The aim of this study was to determine and compare Procalcitonin with other inflammatory markers in the serum of immunosuppressed children with haematological malignancies; and to assess the predictive value of these mediators in distinguishing between bacterial and non-bacterial infection. MET...
Although it is widely considered, in many cases, to involve two separable stages (poor placentation followed by oxidative stress/inflammation), the precise originating causes of preeclampsia (PE) remain elusive. We have previously brought together some of the considerable evidence that a (dormant) microbial component is commonly a significant part of its etiology. However, apart from recognizin...
BACKGROUND Mucopolysaccharidoses are heritable, metabolic diseases caused by deficiency in an activity of one of specific lysosomal enzymes involved in degradation of mucoplysaccharides (glycosaminoglycans). Among many medical problems of patients with mucopolysaccharidoses, there are frequent episodes of diarrhea of unknown etiology. CASE PRESENTATION A girl, diagnosed enzymatically for muco...
The human gut microbiome can modulate metabolic health and affect insulin resistance, and it may play an important role in the etiology of gestational diabetes mellitus (GDM). Here, we compared the gut microbial composition of 43 GDM patients and 81 healthy pregnant women via whole-metagenome shotgun sequencing of their fecal samples, collected at 21-29 weeks, to explore associations between GD...
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