Background: Opioid use disorder is a major concern to public health, and opioid maintenance treatment onmethadone or buprenorphine is a widely used approach. On the other hand, in recent years, there has beenmore regards for the use of opium tincture for detoxification and maintenance treatment of opioiddependence in certain parts...

The magnitude and consequences of prescription opioid (PO) misuse and harms (including rising demand for PO disorder treatment) in Canada have been well-documented. Despite a limited evidence-base for PO dependence treatment, opioid maintenance therapy (OMT) - mostly by means of methadone maintenance treatment (MMT) - has become the de facto first-line treatment for PO-disorders. For example in...

OBJECTIVE Therapeutic approaches for benzodiazepine (BZD) dependence in patients in methadone maintenance treatment (MMT) have met with limited success. Clonazepam detoxification (CDTX) and clonazepam maintenance treatment (CMT) were compared in an open, clinical naturalistic study on such patients. METHODS Benzodiazepine dependent patients substituted their BZD of abuse for clonazepam and we...

BACKGROUND Retention in treatment is a key factor to the success of methadone maintenance treatment (MMT) and considered an important measure in evaluation of treatment effectiveness. OBJECTIVES This study aimed to investigate the retention rate and predictors of retention in MMT in Rafsanjan. PATIENTS AND METHODS This was a historical cohort study. A total of 1396 patients admitted between...

OBJECTIVE Willingness to pay for methadone maintenance treatment (MMT) in three Vietnamese epicentres of injection-drug-driven human immunodeficiency virus (HIV) infection was assessed. METHODS A convenience sample of 1016 patients receiving HIV treatment in seven clinics was enrolled during 2012. Contingent valuation was used to assess willingness to pay. Interviewers reviewed adverse conseq...

Background: In Iran, methadone has been used for methadone maintenance treatment (MMT) as well as analgesic treatment in pain clinics. Recently, there are some reports regarding accidental and intentional methadone poisonings and deaths. The aim of this study was to evaluate the trend of methadone poisonings and deaths during a 10-year period in Tehran, Iran. Methods: This was a retrospective c...

BACKGROUND Vietnam began providing methadone maintenance therapy (MMT) in 2008; as of June 2016, 44,479 persons who inject drugs (PWID) were in treatment in 57 provinces. However, 10-23% of patients were estimated to have dropped out of treatment during the first 2 years. We evaluated dropout and factors associated with quitting treatment. METHODS We followed clients ≥ 18 years old enrolled i...

Background: The present study was conducted with the aim of designing a causal model for the evaluation of sexual dysfunctions based on the variables of methadone dosage and sexual self-concept among individuals undergoing methadone maintenance treatment (MMT).Methods: The study population of the present study consisted of married men of 20 to 45 years of age with sexual ‎relations and undergoi...

BACKGROUND Methadone maintenance treatment (MMT) is widely recognized as an effective method of combatting narcotic addiction. MMT reduces heroin withdrawal symptoms and, thus, makes it possible to provide the psychological and social support that is essential to the rehabilitation of drug users. AIM Compare the severity of depressive symptoms in heroin users who are currently receiving MMT t...