BACKGROUND Nodal metastasis in papillary thyroid cancer (PTC) usually occurs in the central compartment of the ipsilateral neck and spreads laterally. The purpose of this study was to evaluate the diagnostic accuracy of frozen biopsy for quantitative nodal evaluation of central neck metastasis in PTC. METHODS In all, 252 patients with PTC underwent total thyroidectomy with bilateral central n...

BACKGROUND Breast carcinoma rarely metastasizes to the neck, and its management in this area is controversial. There is little published data about whether hormone receptor status changes between primary breast tumors and neck metastasis and whether this influences management. METHODS We evaluated the demographics and treatment of 13 patients presenting with neck metastasis. We used immunoche...

OBJECTIVE This study aimed (1) to investigate the relationship between the presence of lymph node central necrosis, viewed on pre-operative computed tomography imaging, and the occurrence of histopathologically determined metastatic lymph node extracapsular spread and (2) to determine whether a larger scale study would be valuable. MATERIALS AND METHODS Pre-operative computed tomography scans...

BACKGROUND Cervical lymph node metastases of meningioma represent an important diagnostic and treatment challenge. Not only has this entity been rarely described, but successful treatment has never been reported in the literature. METHODS AND RESULTS This case report was conducted using reviews of the literature. A 58-year-old man with a history of resected anaplastic meningioma was referred ...

BACKGROUND Management of the clinically negative neck among patients with oral and oropharyngeal squamous cell carcinoma at the Royal Prince Alfred Hospital, Sydney, Australia has been based on the site and stage of the primary cancer, the likely incidence of microscopic nodal involvement, the treatment modality used for the primary cancer, and whether the neck will be entered during resection ...

BACKGROUND The purpose of this study was to assess whether a positron emission tomography (PET)-directed policy remains appropriate for managing neck nodes (N3; >6 cm) in head and neck squamous cell carcinoma (HNSCC). METHODS All patients with N3 (>6 cm) HNSCC treated with definitive chemoradiotherapy (CRT) at our institution between 2005 and 2012 were included in the analysis. Patients under...

Squamous cell carcinoma of the head and neck (SCCHN) metastasizes predictably to cervical lymph nodes, with low rates of distant metastases. Tumor cells can express various receptors that facilitate such metastatic spread to lymph nodes and other nonlymphoid organs. Chemokine receptors (CCR), normally expressed on lymphocytes, control immune and inflammatory cell migration, providing a link bet...

To cite: Revannasiddaiah S, Sood A, Kumar S, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013010364 DESCRIPTION Within a month of being treated with a partial maxillectomy for a stage T2N0M0 (staged as per preoperative MRI and CT) left maxillary antral carcinoma, a patient suffered symptoms of ‘sore throat’ and also tested positive for a streptococcal i...