We report a case of a 10-year-old girl with a tumour of the right temporoparietal region of the brain. The tumour consisted of three morphologically distinct portions: a well-differentiated one containing a mixture of a ganglioglioma with adipocytic-like cells and focal chondroid metaplasia, a separate island with neurocytic differentiation, and the malignant one, which exhibited an organoid pa...

INTRODUCTION Rarely, the dermatologistmay encounter a primary cutaneous pleomorphic sarcoma (also known as a malignant fibrous histiocytoma), an undifferentiated neoplasm thought to be of mesenchymal origin. These uncommon skin tumors typically manifest as tender subcutaneous nodules. In contrast to primary cutaneous sarcomas, we present a case of a soft tissue pleomorphic sarcomawithmultiple m...

A gastrointestinal stromal tumor (GIST) is a rare malignancy, accounting for only 0.1% to 3% of all (GI) malignancies. Although GISTs are the most common mesenchymal GI tract, they primarily found within stomach, with rectal rarely reported. They may present bleeding, constipation, pain, or palpable mass while some incidentally. The incidence has been on rise, possibly due advancements in diagn...

Abstract Background Primary pediatric liver tumors are scarce. Undifferentiated embryonal sarcoma of the (UESL) embraces nine to fifteen percent hepatic neoplasms. Mesenchymal hamartoma (MHL) is second most prevalent benign neoplasm following infantile hemangioendothelioma. Case presentation A 6-year-old female child presented with vague diffuse abdominal pain and palpable right lumbar mass by ...

INTRODUCTION Mammary-type myofibroblastoma of the soft tissue is a very rare, benign, mesenchymal neoplasm with myofibroblastic differentiation. To date, 20 cases of extra-mammary myofibroblastoma have been described in literature. To the best of our knowledge, this is the largest extra-mammary myofibroblastoma described in the literature, and the first case reported in this location. CASE PR...

Background. Dermatofibrosarcoma protuberans (DFSP) is an intermediate grade soft tissue neoplasm originating from the dermal layer of the skin. It usually occurs in adults; however, it can rarely be seen in infancy and childhood. Diagnosis of DFSP in children is quite difficult-given-rarity of this lesion, its variegated appearance, and its presentation sometimes at unusual sites. Case. We pres...

Abstract Introduction/Objective Lipoblastoma-like tumor of the vulva (LLTV) is a rare, benign mesenchymal neoplasm adipocytic differentiation that typically presents as vulvar mass in young women, clinically mimicking Bartholin gland abnormality. The well-circumscribed and multilobulated, composed mature adipocytes, uniloculated lipoblasts bland spindle cells. Morphologic features often overlap...

Carcinosarcoma of the prostate is a rare neoplasm with malignant epithelial and mesenchymal components. Herein, we report the case of a patient who underwent multiple transurethral resections of the prostate showing adenocarcinoma initially then carcinosarcoma. He underwent a robotic-assisted laparoscopic cystoprostatectomy, bilateral pelvic lymph node dissection, and ileal conduit urinary dive...

Solitary fibrous tumor (SFT) is a ubiquitous rare mesenchymal neoplasm. Pleura is the favored site of origin and is rare in the oral cavity. SFT occurs across a wide histopathologic spectrum. Fibrous form characterized by hyalinized, thick-walled vessels with opened lumina and strong CD34 reactivity constitute one end and on the other end, a cellular form representing the conventional hemangiop...

Even though the diagnosis of schwannoma is usually straightforward in lesions with classic features, tumors with predominantly epithelioid morphology or marked myxoid change may present a diagnostic challenge. There are relatively few reported cases of epithelioid schwannoma entirely lacking classic morphology, and these have occurred in subcutaneous tissues, mucosal surfaces, or as gastrointes...