Introduction: Retinoid signaling has been argued to have favorable effects on Alzheimer's disease (AD). We studied the role of chronic intracerebroventricular (ICV) injection of all-trans retinoic acid (ATRA) on the amyloid-beta (Aβ) model of AD. Methods: Adult male rats weighing 260-330 g were divided into 12 groups of 8 each. Six groups of rats received ATRA (3nM, 30nM, 3μM, 0.3mM, 30...

The development of new technologies has confronted the entire domain of science and industry with issues of big data's scalability as well as its integration with the purpose of forecasting analytics in its life cycle. In predictive analytics, the forecast of near-future and recent past - or in other words, the now-casting - is the continuous study of real-time events and constantly updated whe...

neuropsychological approach tries to link behavior with brain functions. one of the structural changes and functional disorders that is, post-traumatic stress disorder (ptsd). this impaired memory function, learning, emotional processing and cognitive and structural changes in the brain. various aspects of neuropsychological function have been reported to be abnormal in (ptsd); however, the maj...

Memory impairment is one of the main features of post-traumatic stress disorder (PTSD),There are multiple studies in memory impairment and cognitive function such as memory in a variety of explicit memory, implicit, procedural, active, declarative, revermid ,working, visual, false and autobiographical. The methodology of systematic review were, meta-analyzes and controlled studies of sites Med ...

background: multiple sclerosis (ms) is a disease of the immune system that creates damage of learning and memory in that. using probiotic supplements is recommended for preventing ms disease and improving memory. this study aimed to investigate the effect of lactobacillus plantarum (lp) and bifidobacterium b94 (bb94), on acquisition phase of spatial memory in the local demyelination of rats` hi...

objective(s) cyclooxygenases  (coxs) are known to play some roles in physiological mechanisms related to learning and memory. since sodium salicylate is an inhibitor of cox, we have evaluated the effect of peripheral and intra-hippocampal administration of sodium salicylate on spatial learning and memory in male rats. materials and methods male rats were studied in two groups; the first group r...

people with alzheimer disease (ad) have decreases in brain cell function that may increase their risks as drivers. the changes in brain cells affect memory (at first, short-term memory and then much later, long-term memory) and other thinking functions. in addition, people with early ad, though often very functional in many areas of life, may not be as competent behind the wheel of a car as tho...