Objective: The present study investigates the effect of Tiliacora triandra leaf extract on spatial learning, memory, and learning flexibility as well as hippocampal choline acetyltransferase (ChAT) activity in mice.  Materials and Methods: Thirty male ICR mice were randomly divided into three groups including 10% Tween 80, T. triandra 300 mg/kg and T. triandra 600 mg/kg. All administrations wer...

Background: Exposure to electromagnetic radiation may impair memory. This study was conducted to evaluate the effect of radiofrequency wave (hereafter referred to as RFW) on passive avoidance learning and memory in healthy males and females. Materials and Methods: Ten adult male and ten female Sprague-Dawley rats (230±20 gr) were randomly divided into four groups including two control groups (o...

objective(s) we determined the effect of a high fructose diet either alone or in combination with iranian shallot or garlic extract on cognitive functions, plasma lipid profile, and the intraperitoneal glucose tolerance test (ipgtt). materials and methods following induction of insulin resistance in fructose-fed rats (fru-fed), they were randomly assigned to three subgroups. the first subgroup ...

there is strong evidence that two cerebral hemispheres are differentially involved in emotional memory and that amygdala is a key subcortical structure for emotional experience. the present research investigated the possible involvement of lateralization of basolateral amygdala (bla) and central amygdala (cea) in place avoidance memory. for this purpose, male long-evans rats (280-320 g) were im...

background: testosterone and its metabolites have important roles in learning and memory. the current study has conducted to assess the effect of pre-training, post-training and pre-probe trial intrahippocampal ca1 administration of 3 alpha-anderostanediol (one of the metabolites of testosterone) and indomethacin (as 3 alpha-hydroxysteroid dehydrogenase enzyme blocker) on acquisition, consolida...

      Diabetes mellitus is associated with disturbances of learning and memory and cognitive functioning. Aegle marmelos Corr. from Rutaceae family, is widely used in Iranian folk medicine for the treatment of diabetes mellitus. It decreases blood glucose level by improving glucose tolerance and also has lipid-lowering and antioxidant properties. Considering the beneficial antidiabetic...