Gustav Akk has a background in biophysics and pharmacology of ion channels. His current work focuses on the mechanisms of activation and modulation of transmitter-gated ion channels, particularly the GABAA receptor, under physiological and clinical conditions. The GABAA receptor is the major ionotropic inhibitory ion channel in the brain and an important component in the maintenance of excitato...

Meet Our Editorial Board Member Dr. Gerhard Meissner University of Northern Carolina, Chapel Hill, USA The laboratory’s research focuses on defining the molecular basis of Ca release channel (RyR) function in cardiac and skeletal muscle. RyRs are 2,200 kDa ion channels that release Ca ions in response to an action potential from the sarcoplasmic reticulum (SR), an intracellular Ca-storing compa...

Dr. Braunwald received his medical training at New York University and completed his Medical Residency at the Johns Hopkins Hospital. He served as the first Chief of the Cardiology Branch and as Clinical Director of the National Heart, Lung and Blood Institute, founding Chairman of the Department of Medicine at the University of California, San Diego. From 1972 to 1996 he was Chairman of the De...

Her work has been recognized by various honors including the Scientific Prize of Excellence (PES) INSERM. Actually, she drives a team that works for the study of the implication of Parkinson’s disease associated proteins in the origin of cell death in neurodegenerative disorders and tumor suppression. Her research interests include Parkinson’s and Alzheimer’s disease molecular and cell biology,...

His research area includes the mechanism by which prostanoids, small molecules generated by enzymes called cyclooxygenases, are involved in pathological processes. Dr. Boutaud demonstrated for the first time that γ-ketoaldehydes are generated by the cyclooxy-genases during their normal catalytic cycle [1, 2]. Dr. Boutaud further led the effort in characterizing the structure of DNA adducts [3] ...

Aspect-Oriented Software is a broad term, encompassing several different views on the nature of the aspects and the relationships between aspects and objects. Attaching aspects to objects is one way of forming a group. While there are many useful patterns of interaction, e.g. strategies[2], decorators, and the like, we focus on groups in which the group delegates to members to obtain behavior a...

Mycoplasmas recovered from tissue cultures and previously shown to belong to the sterol-nonrequiring group of mycoplasmas have been further characterized. The biological and serological properties of these strains show them to be clearly distinct from Acholeplasma laidlawii and A. granularum, two species of sterol-nonrequiring mycoplasmas recently reclassified. It is proposed that the newly des...

mauddud member with the age of late albian to cenomanian is equivalent to the lower sarvak formation in the southern persian gulf and adjacent area. in this work, microfacies, depositional environment, and diagenetic processes affected the mauddud member in a field in the persian gulf are investigated. based on the studies of available cores and thin sections of 3 wells, five types of microfaci...

Until today there is a research gap considering the question, what motivates a member to enter or leave a co-op, resp. what are the reasons to stay in a co-operative. The majority of studies about this topic mainly focus on economic factors and the rational behavior of the member. However, co-ops also have other purposes not associated with financial goals. The presented paper is proposing a ne...