background: gold nanoparticles (gnps) have been shown as a good radiosensitizer. in combination with radiotherapy, several studies with orthovoltage x-rays have shown considerable dose enhancement effects. this paper reports the dose enhancement factor (def) due to gnps in 18 megavoltage (mv) beams. materials and methods: different geometrical 50-nm gnps configurations at a concentration of 5 m...

The objective of present study was to classify oral mucositis according to the Common Toxicity Criterion (CTC) international parameters in head and neck tumor patients simultaneously treated with radio and chemotherapy, and characterize a patient profile in our area, observing the individuals' habits, tumor characteristics, treatment protocol and acute reaction intensity. Fifty patients undergo...

The purpose of this paper is to describe the reproducibility of liver position using Active Breathing Coordinator in a larger series of patients with more advanced liver cancer, consecutively planned for SBRT delivered in six fractions over two weeks. In this study, repeat megavoltage (MV) verification imaging, real-time beams-eye-view MV movies, conventional kV fluoroscopy, cone beam kV fluoro...

Introduction Deformable image registration (DIR) is used to modify structures according to anatomical changes for observing the dosimetric effect. In this study, megavoltage computed tomography (MVCT) images were used to generate cumulative doses for nasopharyngeal cancer (NPC) patients by various DIR methods. The performance of the multiple DIR methods was analysed, and the impact of dose accu...

The Delta4 biplanar diode array dosimeter was validated for helical tomotherapy delivery QA. The basic detector characteristics were found to be satisfactory in terms of short-term reproducibility (0.1%), linearity (<0.1%), dose rate dependence (0.4%), and absolute calibration accuracy (0.4% in the center of the phantom compared with the independently calibrated diode). Relative calibration of ...

Radiotherapy which consists of external beam radiotherapy (EBRT) and internal radioisotope therapy (RIT), has a wide usage for treating cancer as clinical trials.This study provides some conditions to prove that tungsten oxide nanoparticles (WO3) is a radiosensitizer.The peripheral blood mononuclear cells (PBMCs) were used to calculate inhibitory concentration (IC).The AGS cell line exposed the...