To compare parasitism and inflammatory process in esophagus and colon from chronic chagasic patients, immunohistochemistry was carried out to research for T. cruzi and to evaluate the inflammatory infiltrate in the muscular and myenteric plexus in 39 esophagi (20 with and 19 without megaesophagus) and 50 colons (25 with and 25 without megacolon). The frequency of T. cruzi in megaesophagus was 2...

The dynamism and volatility of a project or a portfolio (frequently changing scope, objectives, priorities, resource allocation, etc) imply that the project can no longer be managed and governed with static or predefined metrics, methodologies, and best practices. As the environment in which a project has to be managed becomes uncertain and unpredictable, it becomes necessary, if not mandatory,...

during pre-project planning as an essential phase of a project, fundamental decisions that lead to project success or failure will make. this phase of a project is more important essentially in oil, gas and petrochemical mega projects that tremendous amount of resources should consume. uncertainty in the initial phases of the project is at the highest level and therefore major project decisions...

Vertebrate claudin proteins are integral components of tight junctions, which function as paracellular diffusion barriers in epithelia. We identified Megatrachea (Mega), a Drosophila transmembrane protein homologous to claudins, and show that it acts in septate junctions, the corresponding structure of invertebrates. Our analysis revealed that Mega has transepithelial barrier function similar t...

BACKGROUND We investigate the usefulness of expressed sequence tags, ESTs, for establishing divergences within the tree of placental mammals. This is done on the example of the established relationships among primates (human), lagomorphs (rabbit), rodents (rat and mouse), artiodactyls (cow), carnivorans (dog) and proboscideans (elephant). METHODOLOGY/PRINCIPAL FINDINGS We have produced 2000 E...

In the era of space commercialization, State is no longer sole actor in international activities; private companies such as SpaceX and OneWeb are now playing huge roles these endeavors. The Mega constellation satellites devised by to provide low‐cost low‐latency internet services remote areas. This large-scale deployment a network large number satellites. Even though this connectivity venture g...

Contemporary urbanization appears as a conundrum especially in developing nations. This study will act as an accelerator to spill out snags caused by urbanization with a new approach in the development of sustainable infrastructure through Public–Private Partnerships (3Ps). This study first explains the complications generated by rapid urbanization in different infrastructural sectors in South ...