OBJECTIVES This study aims to assess the correlation of CT-based structural rigidity analysis with mechanically determined axial rigidity in normal and metabolically diseased rat bone. METHODS A total of 30 rats were divided equally into normal, ovariectomized, and partially nephrectomized groups. Cortical and trabecular bone segments from each animal underwent micro-CT to assess their averag...

Secretion management in the mechanically ventilated patient includes routine methods for maintaining mucociliary function, as well as techniques for secretion removal. Humidification, mobilization of the patient, and airway suctioning are all routine procedures for managing secretions in the ventilated patient. Early ambulation of the post-surgical patient and routine turning of the ventilated ...

BACKGROUND Pain is a common experience among mechanically ventilated patients. Pain among mechanically ventilated patients is aggravated by factors such as stage of illness, invasive procedures, and surgical interventions. The aim to this study was to investigate pain levels and predictors among mechanically ventilated patients during rest and routine nursing interventions. MATERIALS AND METH...

BACKGROUND Several studies have demonstrated that oral care with chlorhexidine gluconate (CHG) 0.12% solution reduces the incidence of ventilator-associated pneumonia (VAP) in mechanically ventilated patients with endotracheal tubes in the ICU. Minimal evidence shows the effectiveness of any oral care protocols in preventing VAP in mechanically ventilated patients with tracheostomies in a step-...

Piezos are mechanically activated ion channels that function as sensors of touch and pressure in various cell types. However, the precise mechanism and structures mediating mechanical activation and subsequent inactivation have not yet been identified. Here we use magnetic nanoparticles as localized transducers of mechanical force in combination with pressure-clamp electrophysiology to identify...

INTRODUCTION Guillain-Barré syndrome (GBS) is an immune-mediated disorder of the peripheral nervous system. Respiratory failure requiring mechanical ventilation (MV) is a serious complication of GBS. Identification of modifiable risk factors for MV and poor short-term prognosis in mechanically ventilated patients with GBS may contribute to the individualized management and may help improve the ...

OBJECTIVE To describe survival outcomes with noninvasive ventilation (NIV) for full ventilatory support, and a mechanically assisted cough and oximetry protocol in a series of patients with Duchenne muscular dystrophy. METHODS We monitored end-tidal carbon dioxide (P(ETCO(2))), S(pO(2)), vital capacity, maximum insufflation capacity, and cough peak flow. Nocturnal NIV was initiated for sympto...

Myogenic constrictor responses in small renal arteries and afferent arterioles are suppressed in mice with reduced levels of β-epithelial Na⁺ channel (βENaC(m/m)). The underlying mechanism is unclear. Decreased activity of voltage-gated calcium channels (VGCC) or mechanically gated ion channels and increased activity of large conductance calcium-activated potassium (BK) channels are a few possi...

Entangled networks of carbon nanofibers are characterized both mechanically and electrically. Results for both tensile and compressive loadings of the entangled networks are presented for various densities. Mechanically, the nanofiber ensembles follow the micromechanical model originally proposed by van Wyk nearly 70 years ago. Interpretations are given on the mechanisms occurring during loadin...

We describe a technique for mechanically proving certain kinds of theorems in combinatorics on words, using automata and a package for manipulating them. We illustrate our technique by solving, purely mechanically, an open problem of Currie and Saari on the lengths of unbordered factors in the Thue-Morse sequence. Dedicated to the memory of Sheng Yu (1950–2012): friend and colleague