Enhanced oxygen reserves in the blood facilitate diving in marine mammals. For pinnipeds (seals and sea lions), a developmental period of 4 to 24 months is required for blood oxygen stores to reach adult capacities. We investigated whether a similar developmental period for the blood occurs in cetaceans (dolphins and whales), a group of mammals that are exposed to diving immediately after birth...

BACKGROUND The anti-inflammatory and antiproliferative agent curcumin has poor oral bioavailability and solubility in plasma. Liposomal formulations have therefore been developed, but the toxicity of these preparations is not yet established. We investigated the influence of free and liposomally formulated curcumin on human red blood cell (RBC) morphology in vitro. MATERIALS AND METHODS EDTA-...

OBJECTIVE To assess iron deficiency or overload in infants with sickle cell disease in order to support the decision to recommend (or not) iron prophylactic supplementation in this population. METHODS Cross-sectional and retrospective study with 135 infants below 2 years old (66 boys and 69 girls), 77 with SS and 58 with SC hemoglobin, born between 2005 and 2006 in Minas Gerais, Brazil. Indic...

This study investigated the hematological parameters of the tropical estuarine fish Centropomus parallelus and their use as a non-destructive biomarker for aquatic pollution. Individuals were collected, in summer and winter, at two estuaries, Cananéia (CAN) and São Vicente (SVE), and blood was extracted by caudal puncture. The evaluated parameters were hematocrit (Ht), red blood cells (RBC), Me...

INTRODUCTION Preoperative anemia and high red cell distribution width (RDW) are associated with higher perioperative mortality. Conditions with high RDW levels can be categorized by mean corpuscular volume (MCV). The relationship between RDW, anemia and MCV may explain causality between high RDW levels and outcomes. We aim to establish the prevalence of preoperative anemia and distribution of R...

Many physiological processes of domestic animals exhibit daily rhythmicity. The goal of the present study was to investigate, in horses, the existence of the daily rhythms of some haematological parameters: red blood cells (RBC), white blood cells (WBC), haemoglobin (Hb), haematocrit (Hct), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH), mean corpuscular haemoglobin concentra...

Alterations in reticulocyte size occur 2-3 days after the onset of iron deficient or megaloblastic erythropoiesis and precede, by several weeks, changes in mean corpuscular volume (MCV). Iron-deficiency anemia induced in a normal subject by repeated phlebotomies was characterized by the initial development of larger than normal reticulocytes followed by an abrupt decrease in reticulocyte size. ...

Background Creutzfeldt–Jakob disease (CJD) is a devastating neurodegenerative caused by propagation of abnormally folded prion proteins (PrPSc). Some fluid biomarkers have been reported to be associated with duration in CJD. Based on studies which found that protein (PrPC) played role erythrocytic hematopoiesis, we evaluated the association between peripheral red blood cell indices and survival...

: Iron deficiency anaemia (IDA) is often associated with congenital heart defect (CHD) in children, especially developing world. Often it remains undiagnosed due to the unaffordability do costly tests like serum ferritin. We have done this study know whether simple test complete hemogram sufficient diagnose IDA a child CHD. This hospital based observational was for period of one and half year p...

Dear Sir: Holland and Forster (1966) demonstrated experimentally that velocity constants for initial rates of oxygen uptake by fully reduced erythrocytes (k~) are inversely related to mean corpuscular volume (MCV) (Table I). They based k" upon measurements of the rate of hemoglobin saturation with oxygen, so that the entire process included oxygen diffusion through the cell membrane, diffusion ...