نتایج جستجو برای: mdr neonatal sepsis
تعداد نتایج: 128118 فیلتر نتایج به سال:
The aim of this cohort (prospective) analytic study was to determine the microbiological pattern of bacterial infection in the Neonatal Intensive Care Unit of Kasr El Eini Hospital, to investigate microbial colonization of neonates at birth before any interference and to examine whether surface cultures yielded information helpful in management. The study population comprised 70 high risk neona...
The epidemiology of nosocomial infections in Turkish neonatal intensive care units (NICUs) shows that nosocomial sepsis is an important problem, especially for very low birth weight (VLBW) infants, and gram-negative agents, particularly Klebsiella species, are still the major causes of nosocomial infections. Sepsis frequency was 6.4%, ranging from 2.1 to 17%, in 16 centers in Turkey. Sepsis fre...
INTRODUCTION Neonatal mortality in developing countries is usually due to an infectious cause. The gold standard of investigation in developing countries is a positive blood culture. It is important to know the aetiology of neonatal bloodstream infections so that empiric treatment can be effective. METHODOLOGY We conducted a retrospective clinical audit over ten years between January 2000 unt...
Background: Sepsis is an important cause of neonatal morbidity and mortality. In Egypt, A multi-center study reported that 45.9% of the neonates admitted to neonatal intensive care units (NICUs) were due to suspected neonatal sepsis. Proper management is not guaranteed due to nonspecific symptoms and signs especially at the onset of disease, delay of culture results and high rate of false negat...
sareshtedari m 1 (md) , shahamat h 1 (md) , sadeghi t 2 * (msc) 1 department of pediatrics, school of medicine, qazvin university of medical sciences, qazvin, iran 2 department of pediatrics, school of nursing and midwifery, tehran university of medical sciences, tehran, iran received: 22 jan 2011, accepted: 23 jun 2011 abstract introduction: regarding the importance of me...
Protein toxins are important virulence factors contributing to neonatal sepsis. The major pathogens of neonatal sepsis, group B Streptococci, Escherichia coli, Listeria monocytogenes, and Staphylococcus aureus, secrete toxins of different molecular nature, which are key for defining the disease. Amongst these toxins are pore-forming exotoxins that are expressed as soluble monomers prior to enga...
Interleukin (IL)-18 is an important effector of innate and adaptive immunity, but its expression must also be tightly regulated because it can potentiate lethal systemic inflammation and death. Healthy and septic human neonates demonstrate elevated serum concentrations of IL-18 compared with adults. Thus, we determined the contribution of IL-18 to lethality and its mechanism in a murine model o...
A prospective observational study was conducted in a neonatal unit of referral teaching hospital North India with an aim to the bacteriological profile and sensitivity pattern referred neonates. During this period one year, incidence culture positive sepsis 34 % among which gram-negative bacilli predominated both early onset late sepsis. In sepsis, predominant organism Klebsiella pneumoniae fol...
OBJECTIVES We determined whether initial antithrombin (AT) levels help in diagnosis and prognosis of neonatal sepsis. METHODS Sepsis was diagnosed according to clinical and laboratory findings and positive culture results in 34 of the 54 newborns who presented to the hospital with suspected sepsis. Between AT levels and hematological parameters (fibrinogen levels, prothrombin time (PT), activ...
Objective: To analyse the Gram-negative bacteriological profile of nosocomial sepsis and antibiotic susceptibility patterns. Methods: Neonates clinically diagnosed with sepsis and whose blood cultures tested positive for Gram-negative microorganisms from 2002 to 2008, retrospectively. Results: 143 cases of neonatal sepsis caused by Gram-negative microorganisms were identified. Eighty-one percen...
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