Background: Heavy metals contaminations are recognized as the serious risk to our environment. The aim of the present study was to analyze heavy metals residue in cultivated mango samples from Iran. Methods: Totally, 72 mango samples were randomly collected among six different mango genotypes cultivated in Southern Iran from June to July 2015. Lead, chromium, cadmium, and arsenic were determin...

PURPOSE In MRL/Mp-lpr/lpr (MRL/lpr) and MRL/Mp-+/+ (MRL/+) mice, a T-cell-driven lacrimal gland inflammation spontaneously develops that is a model for Sjögren's syndrome. The lacrimal gland lesions in these mice were evaluated by immunohistochemistry for the relative contributions of T-helper (Th)1 versus Th2 immune responses. METHODS Frozen sections of lacrimal glands from MRL/lpr and MRL/+...

The aim of the study was a multidimensional analysis occurrence pesticide residues in fruit samples (87) within framework official control (68, WIORiN) and cross-compliance (19, ARiMR). There an assessment frequency detection chemical groups individual active substances (a.s.), level concentrations estimation magnitude exceedances permissible standards (MRLs), as well diagnosis multi-residue sa...

Identification of quantitative trait loci (QTLs) associated with rice root morphology provides useful information for avoiding drought stress and maintaining yield production under the irrigation condition. In this study, a set of chromosome segment substitution lines derived from 9311 as the recipient and Nipponbare as donor, were used to analysis root morphology. By combining the resequencing...

Abstract Autoimmune diseases play a critical role in the progression of infertility both sexes and their severity has been reported to increase with age. However, few reports have discussed effect on morphological features testis. Therefore, we compared alterations testes autoimmune model mice (MRL/MpJ-Fas lpr ) control strain (MRL/MpJ) those background (C57BL/6N) at 3 6 months. Furthermore, an...

INTRODUCTION Systemic lupus erythematosus is associated with a persistent circulation of modified autoantigen-containing apoptotic debris that might be capable of breaking tolerance. We aimed to evaluate apoptotic microvesicles obtained from lupus or control mice for the presence of apoptosis-associated chromatin modifications and for their capacity to stimulate dendritic cells (DC) from lupus ...

The objective of the current study was to evaluate the mechanism of absorption and metabolism of a PEGylated peptide, MRL-1 (46 kDa), after s.c. dosing in dogs and rats. Thoracic lymph ductcannulated (LDC) dog and rat models were developed that allowed continuous collection of lymph for up to 8 days. When [H]MRL-1 was administered s.c. to LDC dogs, ∼73% of the administered radioactivity was rec...

Ecological risk assessment of pesticide residues is not only germane but critical in view their inherent health challenges and for informed decision-making process. This study was conducted to assess the levels contamination organochlorine water from Nwaniba River Uruan Local Government Area Akwa Ibom State. The analysis carried out using Gas Chromatography with electron capture detector (GC-EC...

Problem statement: Mast cells develop from bone marrow-derived progenitor cells and are distributed in the skin or mucosa where they play proinflammatory roles in the first line of defense. Since some tumors in humans and experimental animals exhibited infiltration of increased mast cells, we investigated the contribution of mast cells to the override of tumor rejection. Approach: MRL/N-1 cells...

The P140 peptide, a 21-mer linear peptide (sequence 131-151) generated from the spliceosomal SNRNP70/U1-70K protein, contains a phosphoserine residue at position 140. It significantly ameliorates clinical manifestations in autoimmune patients with systemic lupus erythematosus and enhances survival in MRL/lpr lupus-prone mice. Previous studies showed that after P140 treatment, there is an accumu...