Adult and pediatric patients with ESRD have impaired maximum oxygen consumption (VO(2) max), a reflection of the cardiopulmonary system's ability to meet increased metabolic demands. We sought to determine factors associated with decreased VO(2) max in pediatric patients with different stages of CKD. VO(2) max was measured using a standardized exercise testing protocol in patients with stage 2 ...

Lutzomyia longipalpis expresses a salivary protein called maxadilan (MAX) that functions to dilate vertebrate blood vessels and thereby to facilitate the sand fly's acquisition of blood. We hypothesized that antibodies specific for one of many MAX variants would inhibit vasodilatory function of that variant. In vitro and in vivo experiments showed that antibodies against a specific MAX variant ...

Many organisms exhibit developmental plasticity only in sensitive phases and cannot respond to environmental perturbations at other times. However, we know little about the physiological events that define plastic and canalized phases. During egg production in insects, vitellogenin (Vg) accumulates first in the hemolymph and then in the eggs. In addition, storage proteins may be important resou...

ERWIN Schrödinger (1887–1961) was a distinnetics. There are, however, profound differences beguished physicist who won the Nobel prize in 1933 tween Avery and Schrödinger. Avery conducted biofor his pioneering work on wave mechanics. Yet, to chemical experiments, showing that DNA is the genetic biologists his name is permanently connected with a material. Schrödinger was a theoretical physicist...

The present study describes the isolation of a protein from Escherichia coli possessing kynurenine aminotransferase (KAT) activity and its identification as aspartate aminotransferase (AspAT). KAT catalyses the transamination of kynurenine and 3-hydroxykynurenine to kynurenic acid and xanthurenic acid respectively, and the enzyme activity can be easily detected in E. coli cells. Separation of t...

Multi AXis Differential Optical Absorption Spectroscopy (MAX-DOAS) observations of the oxygen dimer O4 are presented which can serve as a new method for the determination of atmospheric aerosol properties. Like established methods e.g. sun radiometer and LIDAR measurements MAX-DOAS O4 observations determine optical properties of aerosol under atmospheric conditions (not dried). However, the nov...

this study setout to investigate the effect of wheat residue, tillage, and nitrogen fertilizer management on some agronomic traits of soybean as a split split plot based on randomized complete block design with three replications. the main plots included wheat residue management: collecting and leaving residue and sub plot included tillage (without tillage and conventional tillage), and the sub...

To explore the role of the HLH subdomain in bHLHZ proteins, we designed sets of minimalist proteins based on bHLHZ protein Max, bHLH/PAS protein Arnt and bZIP protein C/EBP. In the first, the Max bHLH and C/EBP leucine zipper were fused such that the leucine heptad repeats were not in register; therefore, the protein dimerization interface was disrupted. Max1bHLH-C/EBP showed little ability to ...

  Purpose: This study investigated the effect of endurance activity on brain-derived neurotrophic   factor(BDNF), insulin-like growth factor 1(IGF-1) and its binding protein 3(IGFBP-3) in elderly   healthy individuals.   Materials and Methods: Eleven healthy old males (mean age of 68 ± 2.31 years old, height   of 177 ± 3.1 cm and weight of 79 ± 1.5 kg) were studied. Seventy two hours after maxi...

Pulmonary tuberculosis is a disease caused by Mycobacterium tuberculosis. C-Reactive Protein (CRP) produced in the body liver response to inflammation infection. CRP as main mediator of non-specific immune system, and concentration will increase 1000 times higher than normal value event tissue injury or The aim this study was determine comparison levels phase anti-tuberculosis drug administrati...