This paper develops the notion of temporal abstraction, used originally for the automatic understanding of looping constructs, to account for a class of recursive programs involving side effects upon a relational data base. The programs may involve compositions of several side effects, and these side effects can occur either during descent or upon ascent from recursive calls.

Introduction GMC Guidelines illustrate the importance of documenting key elements of a consultation such as side effects of medication and an assessment of patient’s capacity. Not documenting this information makes a clinician liable if complications arise as there is no evidence of a discussion taking place. Do clinicians document this important information? Our aim was to look for evidence of...

With scientific advances in medical sciences over the years many new diagnostic as well as treatment modalities are developed with many patients getting quality of life which was not available before. On the other hand it is also observed that with advances in medical sciences the patient care is becoming more and more specialized and many new super specialty services coming up. As result of su...

The new technologies that the world races to embrace affect every facet of our lives. But not every new technology makes our lives better. Choosing the wrong technology for an application often has serious and costly side effects. In this document I will examine some of the side effects which have been introduced as computers have become more ubiquitous in educational settings. I will then prop...

162 Journal of Family Planning and Reproductive Health Care 2003: 29(3) Background Inevitably there are limited long-term safety data for any new contraceptive method. Detailed scientific studies, performed in a small number of women, provide evidence on mode of action. Larger clinical trials examine efficacy, side effects and acceptability. The number of women-years of exposure is less than fo...

Objectives: Patients with schizophrenia taking firstor second-generation antipsychotic drugs may switch to treatment with Aripiprazole due to side effects. This atypical antipsychotic launched in Europe in 2004, and has a better reported safety profile. However, patients also discontinue Aripiprazole, despite the lack of a comparable alternative antipsychotic. As very few data are available in ...

PM has the potential to optimize the delivery and dosing of treatments so patients can receive the most benefit at the least amount of risk and harm, eliminating both the unnecessary side effects of toxic treatments such as chemotherapy and the delays associated with the “trial-and-error” process that many patients endure to obtain the correct diagnosis and treatment for their condition. And wh...

“The most fruitful basis for the discovery of a new drug is to start with an old one” is a citation from Sir James Black’s Nobel laureate (1988). The background of this statement lies in the fact that most drugs are able to bind to multiple protein targets in the human body, this is known as polypharmacology. This behaviour can lead to unwanted side effects, and innovative research to avoid suc...

The patterns in this paper describe open source development practices from a performance perspective. In product development, performance is measured in terms of the time it takes to develop a software product, the resulting quality of the software, and the cost of development. These dimensions are in tension with one another. Since improving performance has side effects, we also need to includ...

Minocycline is an antibiotic used increasingly in a variety of situations including MRSA infections and also known for its anti-inflammatory properties. Its side effects are usually benign and well known. We report a first of its kind case of minocycline-associated acute pancreatitis in a patient in whom all other common causes of pancreatitis were ruled out. The aim is to raise awareness about...