Since twins weigh about 20% less than singletons at birth, maternal smoking may be a more severe risk for them than for singletons. Therefore, the effect of maternal smoking during pregnancy on birth weight was investigated in a group of 5376 twins. All necessary information was collected by a questionnaire filled out by the mother of the twins. Gestational age explains more than 75% of the var...

background: improving maternal health is one of the eight millennium development goals (mdgs) aimed at improving maternal healthcare and reducing maternal mortality. the utilization of maternal health services is influenced by several factors that need to be better understood. the objective of this study was to estimate the role of socio-economic position as a determinant of the utilization of ...

A previously unknown class of dominant, maternal-effect lethal M factors was found to be widespread in natural populations of the flour beetle, Tribolium castaneum, collected on several continents. Such factors are integrated into the host chromosomes at variable locations and show the remarkable property of self-selection by maternal-effect lethality to all hatchlings that do not inherit a cop...

Background. Cytomegalovirus (CMV) infection of the fetus is the leading cause of congenital infection. Using the guinea pig model of congenital CMV infection, we sought to determine whether antiviral treatment of a CMVinfected dam could improve the outcome of offspring. Methods. Pregnant Hartley guinea pigs were inoculated with guinea pig CMV (GPCMV) during the late second/early third trimester...

Maternal effects have become an important field of study in evolutionary ecology and there is an ongoing debate regarding their adaptive significance. Some maternal effects can act to increase offspring fitness and are called ‘adaptive maternal effects’. However, other maternal effects decrease offspring fitness and there is confusion regarding whether certain maternal effects are indeed adapti...

OBJECTIVE To evaluate the effect of maternal diabetes on the blood pressure and kidney function of female offspring, as well as if such changes exacerbate during pregnancy. METHODS Diabetes mellitus was induced in female rats with the administration of streptozotocin in a single dose, one week before mating. During pregnancy, blood pressure was measured through plethysmography. On the 20th da...

BACKGROUND Anaemia is a common medical problem in pregnancy. The extent up to which, maternal anaemia effects maternal and neonatal health is still uncertain. Maternal anaemia is commonly considered a risk factor for low birth weight (LBW) babies. Some studies have demonstrated a strong association between low haemoglobin before delivery and LBW babies. However, others have not found a signific...

Primiparous female rats subjected to foot shock and/or immobilization stress were tested for maternal behaviour (MB) by determining the pup retrieval rate (PRR) for 5 minutes. On the third day after parturition PRR significantly decreased when foot shock was given and the fall was more pronounced after immobilization both with and without foot shock. The animals exhibited enhanced MB on the 12t...

During meiosis in human oocytes, chromosome nondisjunction increases with maternal age, leading to disorders such as Down's syndrome. In a recent study in Nature Genetics, Hodges et al. (2005) show that mice with a mutation in the meiosis-specific cohesin protein SMC1beta exhibit age-dependent defects in meiosis. These defects are similar to those observed in oocytes of older human mothers. The...

Variance components for birth, weaning, yearling and final weight in Australian Hereford, Angus and Zebu Cross cattle were estimated by Restricted Maximum Likelihood. Six different animal models were fitted for each trait and breed, ranging from a simple model with animals as the only random effect to the most comprehensive model allowing for both genetic and environmental maternal effects and ...