background rubella is a viral disease with a worldwide distribution. mass vaccination campaigns have increased the vaccine coverage in the world with substantial impact on reduction of rubella infections. in iran, the national measles-rubella campaign, targeting individuals 5-25 years old, was initiated in 2003 and mass childhood vaccination against measles, rubella and mumps has continued ever...

BACKGROUND Varicella outbreaks occur frequently in closed environments such as those of militaries. This paper compares the economic outcomes of varicella vaccination in enlisted servicemen without prior reported varicella infection or vaccination. METHODS We analyzed the economic outcomes of a varicella vaccination program on all enlisted servicemen without prior reported varicella infection...

OBJECTIVE To analyze the cost-effectiveness of a meningococcal C vaccination program in Brazil. METHODS A hypothetical cohort of 3,194,038 children born in Brazil in 2006 was followed for 10 years. A decision tree model was developed using the TreeAge Pro 2007 software program to compare universal infant vaccination with the current program. Epidemiological and cost estimates were based on da...

BACKGROUND There is a need for a rapid and cost-effective evaluation of the effects of different human papillomavirus (HPV) vaccination strategies. Sexually active adolescents are a preferred target group for monitoring, as effects on HPV prevalence would be measurable shortly after implementation of vaccination programs. METHODS The Swedish Chlamydia trachomatis testing program offers free C...

BACKGROUND Despite widespread promotion of quadrivalent human papillomavirus (qHPV) vaccination for young girls, there is limited information on the vaccine's real-world effectiveness and none on the effectiveness of qHPV vaccination programs. We assessed the impact of the qHPV vaccine and Ontario's grade 8 qHPV vaccination program on cervical dysplasia and anogenital warts (AGW). METHODS By ...

BACKGROUND Rotavirus gastroenteritis places a significant health and economic burden on Pakistan. To determine the public health impact of a national rotavirus vaccination program, we performed a cost-effectiveness study from the perspective of the health care system. METHODS A decision tree model was developed to assess the cost-effectiveness of a national vaccination program in Pakistan. Di...

PURPOSE Influenza and pneumococcal vaccines are underused. Systems approaches that incorporate administrative and organizational strategies are more successful than education of providers for improving vaccination rates. Little has been published on the long-term success and durability of such efforts. METHODS We performed a 10-year time-series study to examine the durability and success of a...