Hirschsprung's disease, also known as congenital aganglionic megacolon, is a
congenital disorder which develops due to an absence of neural ganglia in a segment
of large bowel. Most commonly, the rectum or rectosigmoid, and rarely other areas
or the entire colon are involved.
In this disease, all three neural plexi, i.e., the myenteric (Auerbach's) plexus, the
superficial submucosal (Meiss...