Trypoxylon is a genus of solitary crabronid wasps whose population genetics is poorly known. The purpose of the present study was to investigate the genetic variation and differentiation among five populations of Trypoxylon albitarse, a species widely distributed throughout the Neotropics, with records from Panama to northern Argentina. Eight species-specific microsatellite loci were used for g...

Previously, Mantel, Bohidar, and Ciminera (Mantel-Haenszel analyses of litter-matched time-to-response data, with modifi cations for recovery of interlitter information. Cancer Res., 37: 3863-3868, 1977) described how the Mantel-Haenszel method could be applied to litter-matched time-to-tumor data. Each litter would be treated as a separate stratum but only for as long as there remained contras...

AIM In order to assess whether the use of metronidazole during pregnancy is associated with a higher risk of congenital malformations, a meta-analysis was conducted. METHODS All epidemiological studies (cohort and case-control) which estimate risk of congenital malformations after exposure to metronidazole during early pregnancy were included in the meta-analysis. To obtain a summary odds rat...

“This paper was the conception of its junior author, William Haenszel, who had the practical familiarity with the problems of retrospective studies. My experience had been largely in the application of statistics and statistical thinking to laboratory investigations and Haenszel suggested that I augment his own work by any statistical concepts I thought appropriate. Those concepts were, in a wa...

To assess genetic structure and phenotypic diversity of Eupemphix nattereri Steindachner, 1863, morphometric and molecular analyses were carried out for nine populations from the State of Goiás. A total of 11 morphometric traits were evaluated and genetic information was estimated using RAPD markers. Genetic and phenotypic distances were determined as a function of geographical origin. Correlat...

The stratification of patients with acute lymphoblastic leukemia (ALL) into treatment risk groups based on quantification of minimal residual disease (MRD) after induction therapy is now well accepted but the relapse rate of about 20% in intermediate risk patients remains a challenge. The purpose of this study was to further improve stratification by MRD measurement at an earlier stage. MRD was...

We describe a copy-number variant (CNV) for which deletion alleles confer a protective affect against rheumatoid arthritis (RA). This CNV reflects net unit deletions and expansions to a normal two-unit tandem duplication located on human chr12p13.31, a region with conserved synteny to the rat RA susceptibility quantitative trait loci Oia2. Genotyping, using the paralogue ratio test and SNP inte...

Morphological variation in the geographically widespread coral Porites lobata can make it difficult to distinguish from other massive congeneric species. This morphological variation could be attributed to geographic variability, phenotypic plasticity, or a combination of such factors. We examined genetic and microscopic morphological variability in P. lobata samples from the Galápagos, Easter ...

seedless barberry (berberis vulgaris l. var. asperma) is one of the few crops that is only cultivated in eastern parts of iran. as a new crop there has not been any study to identify phylogenetic relationships of this plant with other related species existing in iran. in this study, amplification fragment length polymorphism (aflp) markers based on four selected primer combinations (ecori/tru1i...