نتایج جستجو برای: mannose binding protein
تعداد نتایج: 1451453 فیلتر نتایج به سال:
The binding of drugs by plasma proteins is an important phenomenon, because it influences the size of the free fraction of the drugs in plasma. In this study the influence of dipyridamole (DP) on the protein binding of propranolol (PL) and PL on the protein binding of DP were studied alone and in the presence of nicotine (NC). The equilibrium dialysis was employed for protein bin...
Lectins are carbohydrate-binding proteins broadly used in various therapeutic and biomedical applications. The variable affinity of lectins towards variety carbohydrates has raised attention for the biologist to explore functional aspects lectins. express specificity simple example mannose, lactose, sialic acid, complex glycan, glycoproteins. classified based on their sugar as a tool study prot...
The urokinase-type plasminogen activator receptor (uPAR) plays an important role on the cell surface in mediating extracellular degradative processes and formation of active TGF-beta, and in nonproteolytic events such as cell adhesion, migration, and transmembrane signaling. We have searched for mechanisms that determine the cellular location of uPAR and may participate in its disposal. When us...
The binding of the human immunodeficiency virus (HIV) envelope glycoprotein gp120 to the cell surface receptor CD4 has been considered a primary determinant of viral tropism. A number of cell types, however, can be infected by the virus, or bind gp120, in the absence of CD4 expression. Human placenta was identified as a tissue that binds gp120 in a CD4-independent manner. A placental cDNA libra...
BACKGROUND Mannose-binding lectin is a collectin involved in host defense against infection. Whether mannose-binding lectin deficiency is associated with acute exacerbations of chronic obstructive pulmonary disease is debated. METHODS Participants in a study designed to determine if azithromycin taken daily for one year decreased acute exacerbations had serum mannose-binding lectin concentrat...
The Escherichia coli fimbrial adhesive protein, FimH, mediates shear-dependent binding to mannosylated surfaces via force-enhanced allosteric catch bonds, but the underlying structural mechanism was previously unknown. Here we present the crystal structure of FimH incorporated into the multiprotein fimbrial tip, where the anchoring (pilin) domain of FimH interacts with the mannose-binding (lect...
Immunoglobulin A nephropathy is the most common glomerular disease in China, accounting for about 20 % to 47 of primary diseases. Xiyin liangxue decoction a experience treatment recent years. The research this formula clinical has achieved obvious curative effect. This article aims study protective mechanism xiyin on rats and analyzes compares advantages western medicine with Sprague dawley rat...
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