In recent years, it has been suggested that mandibular malposition, resulting from either malocclusion or improper occlusal reconstruction, is associated with physical complaints, while all stress information is combined at the hypothalamus. In this study, we assessed the hypothalamic activation in a malocclusion model in healthy humans. Eight healthy subjects with normal occlusion participated...

OBJECTIVE Massive bone allografts are frequently used in orthopedic reconstructive surgery, but carry a high failure rate of approximately 25%. We tested whether treatment of graft with mesenchymal stem cells (MSCs) can increase the integration of massive allografts (hemi-mandible) in a large animal model. METHODS Thirty beagle dogs received surgical left-sided hemi-mandibular defects, and th...

In this manuscript there are presented two cases, both with mandibular reconstruction with autograft harvested from the iliac crest, performed more than 40 years ago, but with different bone defect etiology, i.e., mandibular dysplasia and mandibular fracture, both having currently extensive tooth loss in the mandible, being in need for prosthetic rehabilitation. These cases confirm that reconst...

OBJECTIVE To describe the use of radial forearm osteocutaneous free flap in complex mandibular reconstruction. STUDY DESIGN A case series. PLACE AND DURATION OF STUDY Combined Military Hospital, Rawalpindi, from January 1998 to January 2008. METHODOLOGY Patients having a small bony component and a large soft tissue mandibular defect requiring reconstruction were selected. These defects in...

Our aim was to assess the long-term results, complications, and factors associated with failure of mandibular reconstructions among wounded Iraqi civilians with mandibular defects. Success was measured by the quality of bony union, and assessed radiographically and by physical examination. Failures were defined as loss of most or all of the bone graft, or inability to control infection. During ...

In this study, the reasons of breaking of the reconstruction plates used in mandibular continuity or mandibular defects were investigated. The study was conducted on 3 cases in which reconstruction plates were used for tumor resection or invasive wound. The objective was to evaluate the mechanical stress in reconstruction plates by means of the finite element method. Three dimensional model of ...

During the civil war in ex-Yugoslavia, a large number of patients was treated at our clinic for injuries to the lower third of the face.Approximately, one third of them required reconstruction of large and small bone and soft tissue defects of the mandibula. The incidence of war injuries of the maxillofacial structures from 8% to 17%, according to the literature (1). In the ex-Yugoslavia civil ...

BACKGROUND Treatment of intraoral malignant tumors often leads to continuity defects of the mandible. Whereas the use of free vascularised flaps has shortcomings regarding donor site morbidity and a worse-fitting bone geometry, the nonvascularized iliac crest graft could be an alternative option. The purpose of this study was to describe the treatment outcome with nonvascularized iliac crest gr...

OBJECTIVE To review complications and outcomes associated with latissimus-serratus-rib free flap oromandibular and midface reconstruction. DESIGN Retrospective medical record review. SETTING Two academic tertiary care medical centers. PATIENTS Twenty-eight patients with segmental resection of the mandible and 1 patient with combined resection of the mandible and maxilla after excision of ...

The reconstruction of the mandible is a complex procedure because various cosmetic as well as functional challenges must be addressed, including mastication and oral competence. Many surgical techniques have been described to address these challenges, including non-vascularized bone grafts, vascularized bone grafts, and approaches related to tissue engineering. This review summarizes different ...