Figure 1. Ulcerated right thigh lesion and persistent necrotizing soft-tissue infection upon presentation, despite multiple previous debridements (the patient in lithotomy).

Introduction: Tuberculosis is an infectious disease that has displayed increasing incidence in the last decades. It is estimated that up to 20% of tuberculosis cases affect extra-pulmonary organs. In the ENT area, soft palate and tongue are the least probable locations.   Case Report A 62-year-old female with a history of rheumatoid arthritis and treatment with corticosteroids and Adalimumab, d...

introduction: schwannoma, or neurilemmoma, is a benign neoplasm of schwann cells that is extremely rare in the soft palate. herein we present a case of a soft palate schwannoma presenting with an ulcerated surface and purplish colour in a 12 year-old girl. this report also introduces a successful surgical technique for coverage of the defect left by surgery.

Helicobacter pylori (H. pylori) is a pathogen contributing to peptic inflammation, ulceration, and cancer. A crucial step in the pathogenic sequence is when the bacterium first interacts with gastric tissue, an event that is poorly understood in vivo. We have shown that the luminal space adjacent to gastric epithelial damage is a microenvironment, and we hypothesized that this microenvironment ...

Nonsteroidal anti-inflammatory drugs (NSAIDs) can impair gastric ulcer healing. This study investigates the involvement of NSAID-activated gene-1 (NAG-1) in ulcer repair impairment by cyclooxygenase (COX) inhibitors. Gastric ulcers were induced in rats by acetic acid. Four days later, animals received daily intragastric indomethacin (nonselective COX-1/COX-2 inhibitor; 1 mg/kg), 5-(4-chlorophen...

BACKGROUND The natural biomembrane of latex extracted from Hevea brasiliensis has been used as a dressing for skin ulcers. OBJECTIVES To evaluate how safe the natural biomembrane is in relation to hypersensitivity to latex when used as a dressing. METHODS We selected patients with skin ulcers, forming the following groups: control - low occupational exposure to latex (n = 17); latex-exposed...

Ulceration of a cutaneous melanoma on microscopic sections is an adverse prognostic finding. The five-year survival rate is reduced from 80% for non-ulcerated melanomas to 55% in the presence of ulceration for Stage I melanoma patients and from 53 to 12% for Stage II melanoma patients (P less than 0.001). As a group, ulcerated lesions are thicker and more likely to have a nodular growth pattern...

The association between carotid artery disease and stroke has been recognized for more than a century, but the pathophysiology of ischemic events ipsilateral to carotid plaques remains uncertain. Artery-to-artery embolism is one of several mechanisms causing either transient ischemic attacks (TIAs) or stroke ipsilateral to atherosclerotic plaques. Thrombus at the site of arterial occlusion, ath...