Three patients with malignant lymphoma complicated by hypercalaemia without radiological bone abnormality are described. The medical literature has been reviewed and the possible underlying mechansims discussed. The early diagnosis of this potentially fatal complication is important since this may respond (together with the underlying disease) to appropriate chemotherapy.

♦Corresponding Author: Negar Azarpira, MD Transplant Research Center, Pathology Department, Shiraz University of Medical Sciences, Shiraz, Iran Tel/fax:+98-711-6474331 Email:[email protected] Introduction The most common malignancy in the oral cavity is squamous cell carcinoma; however, malignant lymphoma may occur in the lymphoid tissue of Waldeyer's ring, the gingival area, buccal mucos...

Tumor necrosis factor-α-inducible protein-2 (TNFAIP2) is a protein upregulated in cultured cells treated with tumor necrosis factor α (TNF), but its expression in normal and neoplastic tissues remains largely unknown. Here, we use standard immunohistochemical techniques to demonstrate that TNFAIP2 is normally expressed by follicular dendritic cells, interdigitating dendritic cells, and macropha...

Abstract Background Acral vascular syndrome clinically presents as digital ischemia with Raynaud’s phenomenon and erythromelalgia but can be rarely seen in the malignant condition. Patients may present pain, permanent blanching or cyanosis, desquamation ulceration of fingers. is associated lymphoid neoplasm smoking, autoimmune connective tissue diseases, vasculitis. Here, we describe a 79-year-...

Warthin's tumor (WT), so-called adenolymphoma, is a benign salivary gland tumor with both epithelial and lymphoid histological characteristics, so the histogenesis remains unclear. Treatment consists primarily of tumor removal or conservative follow up. Here we present a rare case of malignant lymphoma arising from heterotopic (ectopic) WT. A 102-year-old man presented with a mass in the left s...

Involvement of the ovary by malignant lymphoma is a well-known late manifestation of disseminated nodal disease. Primary ovarian lymphoma is rare. We report a case of primary ovarian non-Hodgkin's lymphoma with bilateral involvement which was managed by surgery and chemotherapy. A 29-year-old woman was admitted with signs and symptoms suggestive of an ovarian cancer. Computed tomography reveale...

Primary lymphomas of the urinary bladder is a fairly uncommon entity, whereas urinary tract involvement is reported in up to 13% of the cases with advanced systemic disease 1 , Primary malignant lymphoma of the urinary bladder was first described in 1885 and marked female preponderance is reported with a female to male ratio of 6.5:1 2 . The most common types of primary lymphoma of the urinary ...

Primary intraocular lymphoma is almost always a central nervous system B-cell non-Hodgkin lymphoma. Primary intraocular lymphoma is commonly diagnosed by demonstrating lymphoma cells in the vitreous or cerebrospinal fluid. An interleukin (IL) 10 to IL-6 ratio greater than 1.0 in these fluids and the detection of immunoglobulin gene rearrangement are useful adjuncts in the diagnosis of primary i...

AIMS To identify occupations suspected to be associated with malignant lymphoma and to generate new hypotheses about occupational risks in a multicentre, population based case control study. METHODS Male and female patients with malignant lymphoma (n = 710) aged 18-80 years of age were prospectively recruited in six study regions in Germany. For each newly recruited lymphoma case, a sex, regi...