Evaporation of micro-liter drops from solid surfaces at room condition is mainly governed by diffusion. Therefore, there should be no difference between evaporation rate of sessile and pendant drops. However, some studies indicate a difference and explain the difference using buoyancy. The objective here is to reconcile the inconsistency in the literature. For that, first, by comparing two iden...

In situ binding of thiol-reactive prodrugs to the cysteine-34 position of circulating albumin is a new approach in drug delivery. Therefore, five maleimide-bearing derivatives of the anticancer drug camptothecin (CPT) were developed as albumin-binding prodrugs. These compounds were synthesized by reacting heterobifunctional cross-linkers based on oligo(ethylene glycols) [3-6 (O-CH(2)-CH(2)) uni...

Sum frequency generation (SFG) vibrational spectroscopy and attenuated total reflectance-Fourier transform infrared spectroscopy (ATR-FTIR) were used to investigate the orientation of N-terminus cysteine-modified cecropin P1 (cCP1) at the polystyrene maleimide (PS-MA)/peptide phosphate buffer solution interface. The cCP1 cysteine group reacts with the maleimide group on the PS-MA surface to che...

The specific conformational states responsible for the unique, reversible temperature- and solvent-driven chiroptical switching process experienced by poly(N-1-naphthyl-N'-octadecyl-carbodiimide) (PNOC) have been identified using VCD spectroscopy and DFT calculations. The distinct VCD spectra of PNOC corresponding to the two specific conformations were obtained for the polymer dissolved in DCM-...

In this paper we find formulas for group inverses of Laplacians of weighted trees. We then develop a relationship between entries of the group inverse and various distance functions on trees. In particular, we show that the maximal and minimal entries on the diagonal of the group inverse correspond to certain pendant vertices of the tree and to a centroid of the tree, respectively. We also give...

Topological metamorphosis represents a powerful approach to modulate the properties of polymers. However, it still remains major challenge achieve tunability bulk mechanical via topological transformation in supramolecular polymer systems. Herein, we couple covalent and single system—referred as covalent-and-supramolecular (CSP)—to realize thermo-responsive macromolecular metamorphosis. The CSP...