First, pubertal development of the penile reflexes, e.g., erections, cups and flips in Wistar-Imamichi male rats was investigated following sheath retraction. Second, the penile reflexes and copulatory behavior in the above males were compared between 10 and 44 weeks of age. The penile reflexes in Wistar-Imamichi rats began to appear from day 26, and all males displayed full components of the r...

We aimed to evaluate the effects of black carrot extract on testicular carboxylesterase (Ces) activity, malondialdehyde (MDA), glutathione S-transferases (GST) and reduced (GSH) in male rats exposed bisphenol A (BPA). Adult Wistar albino were divided into 4 groups as follows (n = 7/group): control, BPA, BPA+Black carrot. Testicular Ces, MDA, GST GSH analyzed by using a spectrophotometer system....

The fruit of Randia monantha is traditionally and empirically used in the preparation a beverage as antivenom for treatment various diseases, but to date there little scientific evidence regarding its antimicrobiological properties toxicity. objective this study was evaluar effect administration aqueous extract pulp on acute toxicity male Wistar rats evaluate antimicrobial activity at different...

Laboratory animals, including rats, play an important role in biomedical research and advances. The human care and management of these animals is an ongoing concern. Since, Trichosomoides infections in rat colonies can interfere with research protocols it is important to know rate of infection and pathology of the infection in the animals used in experimental studies. 275 rats were eviscerated ...

we have studied the ulcerogenic effect of indomethacin in stretozocin. induced diabetic rats. streptozocin (65 mg kg-1) was injected intraperitoneally to male wistar rats. the blood glucose concentration was determined continuously. blood glucose level increased significantly (p<0.001) after 30 days. gastric erosions were induced by intraperitoneal injection of indomethacin (50 mg kg-1) in fast...

Autonomic innervation in the cerebral arterial walls of adult male spontaneously hypertensive rats and of normotensive Wistar-Kyoto rats was studied. When examined by fluorescence microscopy, dense catecholamine fluorescence was observed in anterior cerebral and middle cerebral arteries of both Wistar-Kyoto and spontaneously hypertensive rats. However, vertebral and basilar arteries and small p...

This study was conducted to investigate the mitigation of dietary aflatoxin in Wistar rats using extract from selected phyto-antioxidant sources. A total one hundred and twenty weighing between 180-190g (80 females 40 males) at six weeks old were allotted eight treatments with 15 per treatment (10 5 males), a completely randomized design. The Treatment 1 (Normal diet + no aflatoxin), 2 (Aflatox...

The rising threat of Plasmodium falciparum resistance to Monotherapies has prompted the world health organization (WHO) 2006 guidelines recommend use different anti-malarias. In this study, anti-malaria and hypoglycaemic activities Diosgenin, a potent, yet poorly reported saponin was investigated on P. inoculated Alloxan-Induced, Diabetic Wistar Rats. Fort two (42) adult male wistar rats betwee...

UNLABELLED The renin-angiotensin system plays a crucial role in the regulation of cardiovascular function and maintenance of water-electrolyte balance. The two major receptor types of the system, AT1 and AT2, have different, often opposite effects on these functions. AIM To elucidate the impact of long-term treatment with selective angiotensin receptor antagonists and an agonist on water-salt...

Drug idiosyncrasy is an adverse event of unknown etiology that occurs in a small fraction of people taking a drug. The histamine2 (H2)-receptor antagonist ranitidine causes idiosyncratic reactions in patients. To investigate the hypothesis that ranitidine could induce hematological toxic effects, the drug was administered intraperitoneally (ip) to two of six groups of 200-220 g male Wistar rats...