the objective of this study was to assess the magnitude of the cutaneous leishmaniasis (cl) disease and identification of the causative agent by nested-pcr for current control strategy.this study was carried out as descriptive house-to-house visits in orzoieh district in kerman province, south-east iran, during 2011-2012. a questionnaire was completed for each individual consisting of demograph...

background:  depression is the world’s fourth most prevalent health problem which is ‎associated with substantial mortality, direct medical cost, diminished life quality, and ‎significant physical and psychosocial impairment. this study aimed to investigate the ‎effect of psycho-educational intervention on the life quality of major depressive patients.‎ materials and methods:  sixty patients wh...

this study was carried out to identify the efficacy of caparis spinosa root extract on promastigotes and amastigotes of leishmania major . caparis spinosa extracts were prepared. promastogotes of  l.major (1×10 6 parasites/ml)were incubated at 26 ºc for 24,48 and 72hours in fresh medium(nnn), in absence or presence of different concentrations (0.1,0.3,0.5,0.7,0.9 mg/ml) of caparis spinosa metha...

peripheral blood t lymphocytes and their subsets were studied in 31 patients with beta thalassemia major (age 2-12years) and compared with 14 age-arid sex-matched healthy controls. three monoclonal antibodies (anti-cd3, anti cd-f, unti-cds) were simultaneously applied for detection of th (cd3-, cd4^), tsk (cd3+, cd8+) and th/ts ratio by flow-cytometry respectively. the results of this study sho...

background : historically, leishmanization is the most effective protective measure against cutaneous leishmaniasis (cl), cl lesion induced by leishmanization sometimes takes a long time to heal. ma­nipulation of leishmanization inoculums needed to induce a mild and acceptable cl lesion. the aim of this study was to explore if liposomal form of cpg odn (cytosin phosphate guanin oligodeoxynu­cle...

background: cutaneous leishmaniasis (cl) is a parasitic disease in most parts of iran, especially in the isfahan province. the most common form of cl is a self-healing lesion but in rare situations, infection might develop to non-healing forms. clinical symptoms and treatment process might be influenced by several agents such as host immune response and parasite strains. in this study, the isol...

Sheehan’s syndrome or Simmond’s disease is a rare endocrine disorder seen in clinical practice. The clinical spectrum is diverse and a high index of suspicion together with a good clinical acumen and proper diagnostic approach helps in early diagnosis and prompt treatment of this endocrinopathy. Sheehan’s syndrome presenting as a major depressive disorder finds less mention in the literature.Th...

 Background: Major depression is a common disorder with great social and individual burdens. Transcranial sonography (TCS) is a useful and noninvasive measure for assessment of normal and impaired brain parenchyma. The brainstem raphe nuclei are in close association with dorsocaudal limbic system and plays an important role in depression. In this study we compared the echogenicity of the r...

Background and objectives: Cutaneous leishmaniasis is endemic in most areas of Iran, and the diagnosis of its species is essential for controlling the disease. Leishmania major is the causative agent for cutaneous leishmaniasis in humans. Molecular methods are generally more sensitive than microscopic methods. The present study aimed to use a polymerase chain reaction-enzyme linked immunosorben...