Failure to detect FCD and similar lesions encountered in patients with tuberous sclerosis can have significant clinical consequences, such as preventing surgical intervention for medically refractory epilepsy and misguiding prognostic information regarding cognitive development. Here, we show the beneficial effects on detection of FCD and cortical tubers when using a magnetization transfer T1 s...

Myelin specific imaging techniques to characterize white matter in demyelinating diseases such as multiple sclerosis (MS) have become an area of increasing focus. Gray myelination is important marker cortical microstructure, and its impairment relevant progressive MS. However, assessment challenging due thin layers. While myelin water ultra-short TE not yet been implemented assess myeloarchitec...

Introduction: The goal of this study was to determine the feasibility of performing quantitative magnetization transfer (qMT) at high resolution in the spinal cord on clinical 3T systems. While magnetization transfer (MT) imaging has been used to assess brain tissue microstructure, similar studies in the human spinal cord have been limited. This can largely be attributed to the difficulties ass...

The behavioural and neurofunctional consequences of blindness are becoming increasingly well established, and it has become evident that the amount of reorganization is directly linked to the behavioural adaptations observed in the blind. However investigations of potential neuroanatomical changes resulting from blindness have yielded conflicting results as to the nature of the observed changes...

The behavioural and neurofunctional consequences of blindness are becoming increasingly well established, and it has become evident that the amount of reorganization is directly linked to the behavioural adaptations observed in the blind. However investigations of potential neuroanatomical changes resulting from blindness have yielded conflicting results as to the nature of the observed changes...