In the title centrosymmetric dinuclear nickel complex, [Ni(2)(C(22)H(30)N(4)O(2))(NO(3))(2)], each of the two Ni(II) atoms has a distorted octa-hedral geometry, defined by two N atoms and two O atoms from the macrocyclic ligand and two O atoms from a chelating nitrate anion. The two Ni atoms are bridged by two phenolate O atoms, forming a four-membered Ni(2)O(2) ring.

Understanding the interactions of epothilones with β-tubulin is crucial for computer aided rational design of macrocyclic drugs based on epothilones and epothilone derivatives. Despite numerous structure-activity relationship investigations we still lack substantial knowledge about the binding mode of epothilones and their derivatives to β-tubulin. In this work, we reevaluated the electron crys...

In the macrocyclic centrosymmetric dinuclear complex, [Ag(2)(C(19)H(14)N(6)S(2))(2)](ClO(4))(2), the Ag(I) atom, bis-{[4-(2-pyrid-yl)pyrimidin-2-yl]sulfan-yl}methane (2-bppt) ligand and perchlorate anion each lie on a twofold rotation axis. The 2-bppt ligand chelates two four-coordinated Ag(I) atoms through its two bipyridine-like arms. The O atoms of the perchlorate anion are disordered each o...

Two new sandwich-type lanthanide complexes with the general formula [(Pc)2Ln3(L)(OAc)(OCH3)2] (Ln(3+) = Dy(3+) () and Er(3+) ()) were successfully synthesized and structurally characterized based on closed-macrocyclic Schiff base and phthalocyanine molecules. The magnetic properties and structure-property relationship in this multi-decker system were investigated. Interestingly, the correspondi...

The crystal structure of a naturally occurring cyclic tetrapeptide cyclo(Gly-L-Ser-L-Pro-L-Glu) [cyclo(GSPE)] was obtained. The conformation of synthesized cyclo(GSPE) fixes the coordination to lead ion in a 1:1 ratio. This cyclo(GSPE)-Pb complex was constructed as an asymmetric 3D network in the crystalline state. The polymerization of a heavy metal ion with a rigid asymmetric cyclic tetrapept...

A novel macrocyclic organotin(iv) carboxylate {[n-Bu2Sn(O)]9(CH2CH3)2L}·3CH2CH3OH (complex 1) (L = (9-carboxymethyl-1,3,8,10-tetraoxo-3,8,9,10-tetrahydro-1H-anthra[2,1,9-def;6,5,10-d'e'f']diisoquinolin-2-yl)-acetic acid) was generated by the reaction of dibutyltin oxide with amide dicarboxylic acid L and characterized by elemental analysis, IR, (1)H and (13)C NMR spectroscopy. X-ray crystallogr...

In the crystal structure of the title compound, [Pd2(C36H42N6)Cl2](ClO4)2·2C3H7NO·2CH3OH, the dinuclear Pd(II) complex cation lies on an inversion center. Each Pd(II) ion has a distorted square-planar coordination sphere, defined by three N atoms of the macrocyclic ligand and a chloride ion. The Pd(II) complex cations and the methanol mol-ecules are linked through N-H⋯O and O-H⋯O hydrogen bonds...